Focal Adhesion Network Interactions

Source

Swiss-prot Human Accession

Type

Location

Target

Swiss-prot Human Accession

Type

Location

Effect

Type of Interaction

PMID

1.

Adapter

FACA

Adapter

FAC

0

Binding

2.

Adapter

FACA

ActinBinding

FAC

0

Binding

3.

Adapter

FACA

Adapter

FAC

0

Binding

4.

Adapter

FACA

SerThrKinase

FAC

0

Binding

5.

Adapter

FACA

RasGEF

FACA

0

Binding

6.

Adapter

FACA

GEF

FAC

0

Binding

7.

Adapter

FACA

TyrKinase

FAC

0

Binding

8.

Adapter

FACA

TyrKinase

FAC

0

Binding

9.

TyrKinase

FAC

Adapter

FACA

+

Activation

10.

TyrKinase

FAC

Adapter

FAC

+

Activation

11.

TyrKinase

FAC

Cytoskeletal

FAC

+

Activation

12.

TyrKinase

FAC

Cytoskeletal

FAC

+

Activation

13.

TyrKinase

FAC

Cytoskeletal

FAC

0

Binding

14.

TyrKinase

FAC

Adapter

FAC

0

Binding

15.

TyrKinase

FAC

Cytoskeletal

FAC

+

Activation

16.

TyrKinase

FAC

ActinBinding

FAC

+

Activation

17.

TyrKinase

FAC

GAP

FAC

0

Binding

18.

TyrKinase

FAC

SerThrKinase

FAC

+

Activation

19.

TyrKinase

FAC

Adapter

FAC

+

Activation

20.

TyrKinase

FAC

Adapter

FACA

0

Binding

21.

TyrKinase

FAC

TyrKinase

FAC

0

Binding

22.

TyrKinase

FAC

PtdInsPhosphatase

FAC

0

Binding

23.

TyrKinase

FAC

TyrPhosphatase

FAC

+

Activation

24.

TyrKinase

FAC

E3ligase

FACA

+

Activation

25.

Cytoskeletal

FAC

TyrKinase

FAC

_

Inhibition

26.

Cytoskeletal

FAC

Actinbinding

FAC

0

Binding

27.

Cytoskeletal

FAC

Cytoskeletal

FACA

0

Binding

28.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

29.

Cytoskeletal

FAC

ActinBinding

FAC

0

Binding

30.

Cytoskeletal

FAC

Chaperone

FACA

0

Binding

31.

Cytoskeletal

FAC

ActinBinding

FAC

0

Binding

32.

Cytoskeletal

FAC

ActinBinding

FAC

0

Binding

33.

Cytoskeletal

FAC

SerThrKinase

FAC

0

Binding

34.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

35.

Cytoskeletal

FAC

SerThrKinase

FAC

0

Binding

36.

Cytoskeletal

FAC

Cytoskeletal

FACA

0

Binding

37.

Cytoskeletal

FAC

GAP

FAC

0

Binding

38.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

39.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

40.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

41.

Cytoskeletal

FAC

Phospholipase

FACA

_

Inhibition

42.

Actinbundling

FAC

Cytoskeletal

FAC

0

Binding

43.

Actinbundling

FAC

Cytoskeletal

FACA

0

Binding

44.

Actinbundling

FAC

Adhesion

FAC

0

Binding

45.

Actinbundling

FAC

Adapter

FAC

0

Binding

46.

Actinbundling

FAC

Cytoskeletal

FAC

0

Binding

47.

Actinbundling

FAC

Cytoskeletal

FAC

0

Binding

48.

Actinbundling

FAC

RNAMetabolism

FAC

0

Binding

49.

Actinbundling

FAC

Adhesion

FAC

0

Binding

50.

Actinbundling

FAC

Adapter

FAC

0

Binding

51.

Actinbundling

FAC

Cytoskeletal

FAC

0

Binding

52.

Actinbundling

FAC

Cytoskeletal

FAC

0

Binding

53.

Actinbundling

FAC

Phospholipase

FACA

_

Inhibition

54.

Metalloproteinase

FACA

Adapter

FAC

0

Binding

55.

Metalloproteinase

FACA

Adhesion

FAC

0

Binding

56.

Metalloproteinase

FACA

Adhesion

FAC

0

Binding

57.

Metalloproteinase

FACA

PtdInsKinase

FACA

+

Activation

58.

Metalloproteinase

FACA

Adhesion

FAC

0

Binding

59.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

60.

Cytoskeletal

FAC

Adapter

FAC

0

Binding

61.

SerThrKinase

FACA

Adhesion

FAC

+

Activation

62.

SerThrKinase

FACA

Adapter

FACA

+

Activation

63.

SerThrKinase

FACA

SerThrKinase

FAC

+

Activation

64.

SerThrKinase

FACA

SerThrKinase

FAC

0

Binding

65.

SerThrKinase

FACA

TyrPhosphatase

FACA

_

Inhibition

66.

SerThrKinase

FACA

GTPase

FACA

+

Activation

67.

SerThrKinase

FACA

SerThrKinase

FAC

+

Activation

68.

SerThrKinase

FACA

ActinBinding

FAC

+

Activation

69.

GEF

FACA

GTPase

FACA

+

Activation

70.

GEF

FACA

Cytoskeletal

FAC

0

Binding

71.

GEF

FACA

Cytoskeletal

FAC

0

Binding

72.

GEF

FACA

PtdInsKinase

FACA

+

Activation

73.

GEF

FACA

SerThrKinase

FAC

+

Activation

74.

GTPase

FACA

Adapter

FAC

0

Binding

75.

GTPase

FACA

Phospholipase

FACA

+

Activation

76.

Adapter

FAC

E3ligase

FACA

0

Binding

77.

Adapter

FAC

GTPase

FAC

0

Binding

78.

Adapter

FAC

TyrKinase

FAC

0

Binding

79.

Adapter

FAC

Actinbundling

FAC

0

Binding

80.

Adapter

FAC

Cytoskeletal

FAC

0

Binding

81.

ActinBinding

FACA

Cytoskeletal

FAC

+

Activation

82.

ActinBinding

FACA

Actinbinding

FAC

0

Binding

83.

ActinBinding

FACA

GEF

FACA

0

Binding

84.

ActinBinding

FACA

Cytoskeletal

FAC

0

Binding

85.

GAP

FAC

GTPase

FACA

_

Inhibition

86.

GAP

FAC

Actinbinding

FAC

0

Binding

87.

GAP

FAC

TyrKinase

FAC

0

Binding

88.

GAP

FAC

Adapter

FAC

0

Binding

89.

GEF

FACA

Cytoskeletal

FAC

0

Binding

90.

GEF

FACA

Cytoskeletal

FAC

0

Binding

91.

GEF

FACA

Adapter

FAC

0

Binding

92.

GEF

FACA

Adapter

FAC

0

Binding

93.

GEF

FACA

Adapter

FACA

0

Binding

94.

CysProtease

FACA

SerThrKinase

FAC

_

Inhibition

95.

CysProtease

FACA

Actinbundling

FAC

_

Inhibition

96.

CysProtease

FACA

Actinbinding

FAC

_

Inhibition

97.

CysProtease

FACA

Cytoskeletal

FAC

_

Inhibition

98.

CysProtease

FACA

TyrKinase

FAC

_

Inhibition

99.

CysProtease

FACA

ActinBinding

FAC

_

Inhibition

100.

CysProtease

FACA

Adhesion

FAC

_

Inhibition

101.

CysProtease

FACA

ActinBundling

FACA

_

Inhibition

102.

CysProtease

FACA

Adapter

FAC

_

Inhibition

103.

CysProtease

FACA

GEF

FAC

0

Binding

104.

CysProtease

FACA

TyrPhosphatase

FACA

_

Inhibition

105.

CysProtease

FACA

GTPase

FACA

_

Inhibition

106.

CysProtease

FACA

TyrPhosphatase

FAC

_

Inhibition

107.

CysProtease

FACA

TyrKinase

FAC

_

Inhibition

108.

CysProtease

FACA

Cytoskeletal

FAC

_

Inhibition

109.

CysProtease

FACA

Cytoskeletal

FAC

_

Inhibition

110.

CysProtease

FACA

Cytoskeletal

FAC

_

Inhibition

111.

CysProtease

FACA

E3ligase

FACA

_

Inhibition

112.

Chaperone

FAC

Adhesion

FAC

0

Binding

113.

Chaperone

FAC

Receptor

FAC

0

Binding

114.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

115.

Cytoskeletal

FAC

Adapter

FAC

0

Binding

116.

Cytoskeletal

FAC

TyrKinase

FAC

0

Binding

117.

Cytoskeletal

FAC

Adapter

FACA

0

Binding

118.

Cytoskeletal

FAC

TyrKinase

FACA

0

Binding

119.

Cytoskeletal

FAC

TyrKinase

FAC

0

Binding

120.

Cytoskeletal

FAC

Adapter

FAC

0

Binding

121.

Cytoskeletal

FAC

PtdInsKinase

FACA

0

Binding

122.

Cytoskeletal

FAC

TyrKinase

FAC

0

Binding

123.

Cytoskeletal

FAC

GTPase

FAC

0

Binding

124.

Cytoskeletal

FAC

ActinBinding

FAC

0

Binding

125.

Cytoskeletal

FAC

Adapter

FAC

0

Binding

126.

Cytoskeletal

FAC

Channel

FACA

0

Binding

127.

Cytoskeletal

FAC

SerThrKinase

FAC

0

Binding

128.

Cytoskeletal

FAC

Receptor

FACA

0

Binding

129.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

130.

Cytoskeletal

FAC

SerThrPhosphatase

FAC

_

Inhibition

131.

Cytoskeletal

FAC

PtdInsPhosphatase

FACA

0

Binding

132.

Cytoskeletal

FAC

TyrPhosphatase

FACA

0

Binding

133.

Cytoskeletal

FAC

Receptor

FACA

0

Binding

134.

E3ligase

FACA

Adhesion

FAC

_

Inhibition

135.

E3ligase

FACA

TyrKinase

FAC

_

Inhibition

136.

E3ligase

FACA

Adapter

FAC

0

Binding

137.

E3ligase

FACA

Cytoskeletal

FAC

0

Binding

138.

E3ligase

FACA

Adapter

FAC

0

Binding

139.

E3ligase

FACA

GTPase

FAC

0

Binding

140.

E3ligase

FACA

Adapter

FAC

0

Binding

141.

E3ligase

FACA

PtdInsKinase

FACA

_

Inhibition

142.

E3ligase

FACA

PtdInsKinase

FAC

0

Binding

143.

E3ligase

FACA

TyrKinase

FAC

0

Binding

144.

E3ligase

FACA

Adapter

FAC

0

Binding

145.

E3ligase

FACA

Adapter

FACA

0

Binding

146.

E3ligase

FACA

PtdInsPhosphatase

FAC

0

Binding

147.

E3ligase

FACA

TyrKinase

FAC

0

Binding

148.

E3ligase

FACA

TyrKinase

FACA

_

Inhibition

149.

E3ligase

FACA

Cytoskeletal

FACA

0

Binding

150.

E3ligase

FACA

GEF

FACA

_

Inhibition

151.

Adhesion

FACA

ActinBinding

FAC

0

Binding

152.

Adhesion

FACA

Adapter

FAC

0

Binding

153.

Adhesion

FACA

Adapter

FACA

0

Binding

154.

Adhesion

FACA

TyrPhosphatase

FAC

0

Binding

155.

Adhesion

FACA

TyrPhosphatase

FAC

0

Binding

156.

Adhesion

FACA

Cytoskeletal

FAC

0

Binding

157.

Adapter

FAC

PtdInsPhosphatase

FAC

0

Binding

158.

Adapter

FAC

GAP

FAC

0

Binding

159.

Adapter

FAC

Adapter

FAC

0

Binding

160.

Adapter

FAC

PtdInsKinase

FACA

0

Binding

161.

Adapter

FAC

RasGEF

FACA

0

Binding

162.

ActinBinding

FACA

Cytoskeletal

FAC

0

Binding

163.

Actinbinding

FAC

Cytoskeletal

FAC

0

Binding

164.

Actinbinding

FAC

GTPase

FAC

0

Binding

165.

Cytoskeletal

FAC

GEF

FAC

0

Binding

166.

Cytoskeletal

FAC

GEF

FAC

0

Binding

167.

Cytoskeletal

FAC

Adapter

FAC

0

Binding

168.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

169.

Cytoskeletal

FAC

SerThrKinase

FACA

0

Binding

170.

Cytoskeletal

FAC

Adapter

FAC

0

Binding

171.

Cytoskeletal

FAC

GAP

FACA

0

Binding

172.

Cytoskeletal

FAC

Adapter

FACA

0

Binding

173.

Cytoskeletal

FAC

RasGEF

FACA

0

Binding

174.

Cytoskeletal

FAC

GEF

FACA

0

Binding

175.

Adapter

FAC

Cytoskeletal

FAC

0

Binding

176.

Adapter

FAC

Adapter

FAC

0

Binding

177.

Adapter

FAC

GAP

FACA

0

Binding

178.

Adapter

FAC

Adapter

FACA

0

Binding

179.

Adapter

FAC

RasGEF

FACA

0

Binding

180.

Adapter

FAC

TyrKinase

FACA

0

Binding

181.

Cytoskeletal

FACA

Cytoskeletal

FAC

0

Binding

182.

TyrKinase

FAC

TyrKinase

FAC

0

Binding

183.

TyrKinase

FAC

TyrKinase

FACA

+

Activation

184.

TyrKinase

FAC

Adapter

FAC

0

Binding

185.

TyrKinase

FAC

Receptor

FACA

0

Binding

186.

TyrKinase

FAC

Adapter

FACA

+

Activation

187.

TyrKinase

FAC

TyrKinase

FACA

+

Activation

188.

TyrKinase

FAC

Adapter

FAC

0

Binding

189.

TyrKinase

FAC

TyrPhosphatase

FAC

0

Binding

190.

TyrKinase

FAC

TyrKinase

FAC

+

Activation

191.

NA

Lipid

FACA

SerThrKinase

FAC

+

Activation

192.

GEF

FAC

GEF

FAC

0

Binding

193.

GEF

FAC

Adapter

FAC

0

Binding

194.

GEF

FAC

GTPase

FACA

+

Activation

195.

GTPase

FAC

TyrKinase

FAC

0

Binding

196.

GTPase

FAC

Adapter

FAC

0

Binding

197.

GTPase

FAC

Adapter

FAC

0

Binding

198.

GTPase

FAC

PtdInsKinase

FAC

0

Binding

199.

GTPase

FAC

ActinBinding

FACA

0

Binding

200.

GTPase

FAC

Adhesion

FAC

0

Binding

201.

GTPase

FAC

Cytoskeletal

FACA

0

Binding

202.

GTPase

FAC

GEF

FACA

0

Binding

203.

GEF

FAC

GTPase

FACA

+

Activation

204.

Adhesion

FACA

Adapter

FAC

0

Binding

205.

Adhesion

FACA

Cytoskeletal

FAC

0

Binding

206.

TF

FAC

Adhesion

FAC

0

Binding

207.

SerThrKinase

FACA

CysProtease

FACA

+

Activation

208.

SerThrKinase

FACA

Adapter

FAC

+

Activation

209.

SerThrKinase

FACA

Cytoskeletal

FAC

+

Activation

210.

SerThrKinase

FACA

RasGEF

FACA

+

Activation

211.

SerThrKinase

FACA

GEF

FACA

+

Activation

212.

SerThrKinase

FACA

SerThrKinase

FAC

+

Activation

213.

SerThrKinase

FACA

Adhesion

FAC

0

Binding

214.

Cytoskeletal

FAC

TyrKinase

FAC

0

Binding

215.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

216.

Cytoskeletal

FAC

Exchanger

FACA

0

Binding

217.

Cytoskeletal

FAC

Cytoskeletal

FAC

0

Binding

218.

Cytoskeletal

FAC

PtdInsKinase

FACA

0

Binding

219.

Cytoskeletal

FAC

SerThrKinase

FAC

0

Binding

220.

Cytoskeletal

FAC

Adhesion

FAC

0

Binding

221.

TyrKinase

FAC

Actinbundling

FAC

+

Activation

222.

TyrKinase

FAC

Adapter

FAC

0

Binding

223.

TyrKinase

FAC

Adapter

FAC

0

Binding

224.

TyrKinase

FAC

TyrKinase

FACA

0

Binding

225.

TyrKinase

FAC

GAP

FAC

+

Activation

226.

TyrKinase

FAC

GAP

FAC

0

Binding

227.

TyrKinase

FAC

Adapter

FAC

0

Binding

228.

TyrKinase

FAC

Adapter

FAC

+

Activation

229.

TyrKinase

FAC

Cytoskeletal

FAC

0

Binding

230.

TyrKinase

FAC

Channel

FACA

0

Binding

231.

TyrKinase

FAC

Adapter

FAC

0

Binding

232.

TyrKinase

FAC

Chaperone

FACA

0

Binding

233.

TyrKinase

FAC

Adhesion

FAC

0

Binding

234.

TyrKinase

FAC

Adhesion

FAC

0

Binding

235.

TyrKinase

FAC

Adapter