Focal Adhesion Network Components
The network contain 156 biomolecular components, including 25 adaptors, 24 cytoskeletal,10 serine/threonine kinases, 3 serine/threonine phosphatases, 9 actin binding proteins, 9 tyrosine phosphatases, 8 GAPs, 8 GEFs, 8 tyrosine kinases, 7 receptors, 6 adhesion proteins, 5 GTPase and 32 other types of components. 91 components are bona-fide focal adhesion components while 65 are considered focal adhesion associated.
| Name | Type | Location | Links | In Links | Out Links | CC | Avg. Path Length |
| ABI1 | Adapter | FACA | 9 | 1 | 0 | 0.305556 | 2.45806 |
| ABL1 | TyrKinase | FAC | 19 | 5 | 10 | 0.210526 | 2.11613 |
| ACTB | Cytoskeletal | FAC | 23 | 1 | 2 | 0.0750988 | 2.19355 |
| ACTN1 | Actinbundling | FAC | 18 | 5 | 1 | 0.104575 | 2.2 |
| ADAM12 | Metalloproteinase | FACA | 6 | 1 | 1 | 0.266667 | 2.48387 |
| AKT1 | SerThrKinase | FACA | 12 | 5 | 7 | 0.318182 | 2.23226 |
| ARF1 | GTPase | FACA | 5 | 3 | 1 | 0.3 | 2.68387 |
| ARHGAP24 | GAP | FAC | 2 | 0 | 1 | 0 | 2.98065 |
| ARHGAP26 | GAP | FAC | 3 | 0 | 1 | 0.333333 | 2.69032 |
| ARHGAP5 | GAP | FACA | 1 | 0 | 1 | 0 | 3.41935 |
| ARHGEF6 | GEF | FAC | 9 | 1 | 2 | 0.222222 | 2.36774 |
| ARPC2 | ActinBinding | FACA | 4 | 0 | 1 | 0.333333 | 2.85161 |
| BCAR1 | Cytoskeletal | FAC | 21 | 9 | 0 | 0.195238 | 2.23226 |
| BCAR3 | GEF | FACA | 5 | 0 | 3 | 0.3 | 2.64516 |
| C20orf42 | Cytoskeletal | FAC | 1 | 0 | 0 | 0 | 2.96129 |
| Calcium | Messenger | FACA | 3 | 2 | 1 | 0 | 2.97419 |
| CALR | Chaperone | FAC | 2 | 0 | 0 | 0 | 3.28387 |
| CAPN1 | CysProtease | FACA | 21 | 4 | 17 | 0.2 | 2.0129 |
| CAV1 | Cytoskeletal | FAC | 14 | 2 | 1 | 0.0659341 | 2.29677 |
| CBL | E3ligase | FACA | 26 | 9 | 5 | 0.258462 | 2.10323 |
| CD47 | Receptor | FACA | 3 | 0 | 0 | 0 | 2.89677 |
| CEACAM1 | Adhesion | FACA | 6 | 0 | 0 | 0.133333 | 2.52903 |
| CFL1 | ActinBinding | FACA | 4 | 3 | 0 | 0 | 2.89032 |
| CRK | Cytoskeletal | FAC | 17 | 0 | 0 | 0.183824 | 2.29032 |
| CRKL | Adapter | FAC | 12 | 0 | 0 | 0.212121 | 2.4 |
| CSK | TyrKinase | FAC | 11 | 1 | 4 | 0.309091 | 2.32258 |
| CSRP1 | Cytoskeletal | FACA | 3 | 0 | 0 | 0.666667 | 2.89677 |
| CTTN | Actinbinding | FAC | 9 | 4 | 0 | 0.138889 | 2.33548 |
| DAG | Lipid | FACA | 2 | 1 | 1 | 1 | 2.76774 |
| DDEF1 | GAP | FAC | 8 | 3 | 1 | 0.357143 | 2.32903 |
| DDEF2 | GAP | FAC | 3 | 1 | 1 | 0.666667 | 2.8 |
| DMN | Adapter | FAC | 2 | 0 | 0 | 0 | 3.16129 |
| DNM2 | GTPase | FAC | 13 | 1 | 0 | 0.153846 | 2.32903 |
| DOCK1 | GEF | FAC | 4 | 0 | 1 | 0.5 | 2.91613 |
| ELMO1 | GEF | FAC | 3 | 0 | 1 | 1 | 3.0129 |
| ENAH | ActinBinding | FAC | 3 | 0 | 0 | 0 | 3.13548 |
| ENG | Adhesion | FACA | 2 | 0 | 0 | 0 | 3.40645 |
| FBLIM1 | Cytoskeletal | FAC | 3 | 0 | 0 | 0 | 3.03226 |
| FHL2 | Adapter | FAC | 3 | 0 | 0 | 0.666667 | 2.66452 |
| FLNA | ActinBinding | FAC | 16 | 5 | 0 | 0.133333 | 2.19355 |
| FYN | TyrKinase | FACA | 23 | 3 | 13 | 0.209486 | 2.09032 |
| GAB1 | Adaptor | FAC | 8 | 2 | 0 | 0.357143 | 2.53548 |
| GIT1 | GAP | FAC | 11 | 2 | 1 | 0.236364 | 2.25806 |
| GNB2L1 | Adapter | FAC | 6 | 0 | 1 | 0.6 | 2.4129 |
| GRB2 | Adapter | FAC | 26 | 1 | 0 | 0.236923 | 2.16774 |
| GRB7 | Adapter | FAC | 3 | 1 | 0 | 0.666667 | 2.69032 |
| HRAS | GTPase | FACA | 6 | 3 | 2 | 0.266667 | 2.76129 |
| HSPA2 | Chaperone | FACA | 2 | 0 | 0 | 1 | 2.65806 |
| HSPB1 | Chaperone | FACA | 2 | 0 | 0 | 0 | 2.9871 |
| ILK | SerThrKinase | FAC | 9 | 2 | 1 | 0.111111 | 2.49032 |
| ILKAP | SerThrPhosphatase | FACA | 1 | 0 | 0 | 0 | 3.48387 |
| INPP5D | PtdInsPhosphatase | FAC | 8 | 0 | 1 | 0.285714 | 2.64516 |
| INPPL1 | PtdInsPhosphatase | FAC | 7 | 1 | 1 | 0.238095 | 2.47742 |
| INSR | Receptor | FACA | 18 | 3 | 10 | 0.215686 | 2.25161 |
| IP3 | Lipid | FACA | 2 | 1 | 1 | 0 | 3.11613 |
| IRS1 | Adapter | FACA | 11 | 7 | 0 | 0.345455 | 2.36129 |
| ITGA5 | Adhesion | FAC | 13 | 1 | 1 | 0.0641026 | 2.40645 |
| ITGB1 | Adhesion | FAC | 31 | 7 | 0 | 0.133333 | 1.96774 |
| ITGB3BP | TF | FAC | 1 | 0 | 0 | 0 | 2.96129 |
| JUB | Cytoskeletal | FAC | 2 | 0 | 0 | 0 | 3.02581 |
| KALPHA1 | Cytoskeletal | FACA | 7 | 1 | 0 | 0.571429 | 2.51613 |
| KCNH2 | Channel | FACA | 3 | 0 | 0 | 0.333333 | 2.65161 |
| KEAP1 | ActinBundling | FAC | 1 | 0 | 0 | 0 | 3.1871 |
| KTN1 | Receptor | FAC | 2 | 2 | 0 | 0 | 3.12903 |
| LASP1 | ActinBinding | FAC | 7 | 2 | 0 | 0.285714 | 2.65806 |
| LAYN | Receptor | FACA | 2 | 0 | 0 | 0 | 3.09677 |
| LIMK1 | SerThrKinase | FACA | 3 | 2 | 1 | 0 | 3.08387 |
| LIMS1 | Adapter | FAC | 2 | 0 | 0 | 0 | 3.20645 |
| LPP | Adapter | FAC | 3 | 0 | 0 | 0.333333 | 3.03871 |
| LPXN | Adapter | FAC | 4 | 0 | 0 | 0.5 | 2.70968 |
| LRP1 | Receptor | FAC | 3 | 1 | 0 | 0.333333 | 2.78065 |
| LYN | TyrKinase | FACA | 13 | 1 | 5 | 0.384615 | 2.28387 |
| MAPK1 | SerThrKinase | FACA | 8 | 0 | 6 | 0.25 | 2.38065 |
| MAPK8 | SerThrKinase | FACA | 5 | 0 | 3 | 0.1 | 2.72903 |
| MAPK8IP3 | Adapter | FACA | 4 | 1 | 0 | 0.5 | 2.56774 |
| MARCKS | ActinBundling | FACA | 2 | 2 | 0 | 1 | 2.74839 |
| NCK2 | Adapter | FAC | 9 | 0 | 0 | 0.194444 | 2.45806 |
| NEDD9 | Cytoskeletal | FAC | 11 | 3 | 0 | 0.236364 | 2.41935 |
| NEXN | ActinBinding | FAC | 1 | 0 | 0 | 0 | 3.1871 |
| NF2 | Cytoskeletal | FAC | 5 | 0 | 1 | 0 | 2.56129 |
| NUDT16L1 | Adapter | FAC | 3 | 0 | 0 | 0 | 2.7871 |
| OSTF1 | Adapter | FAC | 2 | 1 | 0 | 1 | 2.77419 |
| p190GAP | NA | NA | 6 | 3 | 1 | 0.4 | 2.37419 |
| P190GAP | NA | NA | 2 | 1 | 1 | 0 | 2.87097 |
| PABPC1 | RNAMetabolism | FACA | 1 | 0 | 0 | 0 | 2.94194 |
| PAK1 | SerThrKinase | FAC | 19 | 8 | 4 | 0.0994152 | 2.2 |
| PALLD | Cytoskeletal | FAC | 6 | 0 | 0 | 0.2 | 2.87097 |
| PARVA | Cytoskeletal | FAC | 4 | 0 | 1 | 0.166667 | 2.59355 |
| PARVB | Cytoskeletal | FAC | 3 | 0 | 0 | 0 | 2.89032 |
| PDPK1 | SerThrKinase | FAC | 6 | 1 | 4 | 0.6 | 2.38065 |
| PFN1 | ActinBinding | FACA | 6 | 1 | 0 | 0.133333 | 2.78065 |
| PIK3CA | PtdInsKinase | FACA | 22 | 5 | 4 | 0.242424 | 2.19355 |
| PIP2 | Lipid | FACA | 13 | 2 | 11 | 0.115385 | 2.45806 |
| PIP3 | Lipid | FACA | 8 | 4 | 4 | 0.107143 | 2.52903 |
| PIP5K1C | PtdInsKinase | FACA | 7 | 3 | 1 | 0.238095 | 2.43871 |
| PKD1 | Channel | FAC | 5 | 1 | 0 | 0.4 | 2.54839 |
| PLAUR | Receptor | FACA | 3 | 0 | 0 | 0 | 2.83871 |
| PLCG1 | PtdInsKinase | FAC | 19 | 6 | 2 | 0.298246 | 2.16129 |
| PLD1 | Phospholipase | FACA | 9 | 7 | 1 | 0.222222 | 2.37419 |
| PLEC1 | Cytoskeletal | FACA | 3 | 0 | 0 | 0 | 2.72903 |
| PLEKHC1 | Cytoskeletal | FAC | 1 | 0 | 0 | 0 | 4.02581 |
| PPFIA1 | Adapter | FAC | 2 | 0 | 0 | 0 | 3.1871 |
| PPM1M | SerThrPhosphatase | FAC | 2 | 0 | 1 | 1 | 3.04516 |
| PPP2CA | SerThrPhosphatase | FAC | 9 | 1 | 7 | 0.166667 | 2.28387 |
| PRKACA | SerThrKinase | FACA | 9 | 0 | 9 | 0.277778 | 2.34194 |
| PRKCA | SerThrKinase | FAC | 36 | 11 | 23 | 0.142857 | 1.87742 |
| PTEN | PtdInsPhosphatase | FACA | 5 | 1 | 3 | 0.1 | 2.56774 |
| PTK2 | TyrKinase | FAC | 42 | 7 | 7 | 0.135889 | 1.86452 |
| PTK2B | TyrKinase | FAC | 24 | 3 | 6 | 0.271739 | 2.10323 |
| PTPN1 | TyrPhosphatase | FACA | 10 | 4 | 5 | 0.244444 | 2.26452 |
| PTPN11 | TyrPhosphatase | FAC | 14 | 3 | 7 | 0.32967 | 2.26452 |
| PTPN12 | TyrPhosphatase | FAC | 15 | 2 | 7 | 0.2 | 2.24516 |
| PTPN2 | TyrPhosphatase | FACA | 4 | 1 | 3 | 0.333333 | 2.69677 |
| PTPN6 | TyrPhosphatase | FAC | 15 | 6 | 5 | 0.247619 | 2.23871 |
| PTPRA | TyrPhosphatase | FAC | 6 | 2 | 3 | 0.6 | 2.45161 |
| PTPRF | TyrPhosphatase | FAC | 5 | 1 | 3 | 0.1 | 2.77419 |
| PTPRH | TyrPhosphatase | FACA | 3 | 0 | 3 | 1 | 2.58065 |
| PTPRO | TyrPhosphatase | FACA | 1 | 0 | 1 | 0 | 2.94194 |
| PXN | Adapter | FAC | 36 | 11 | 0 | 0.104762 | 1.94839 |
| RAC1 | GTPase | FACA | 21 | 12 | 6 | 0.0857143 | 2.27097 |
| RAPGEF1 | GEF | FACA | 6 | 1 | 0 | 0.6 | 2.63226 |
| RASA1 | GAP | FAC | 7 | 2 | 1 | 0.333333 | 2.46452 |
| RAVER1 | RNAMetabolism | FAC | 2 | 0 | 0 | 1 | 2.9871 |
| RHOA | GTPase | FACA | 15 | 8 | 7 | 0.0761905 | 2.42581 |
| RICS | GAP | FACA | 8 | 2 | 2 | 0.214286 | 2.52903 |
| ROCK1 | SerThrKinase | FACA | 6 | 1 | 4 | 0 | 2.79355 |
| SDC4 | Adhesion | FAC | 9 | 3 | 0 | 0.138889 | 2.47097 |
| SDCBP | Cytoskeletal | FAC | 3 | 1 | 0 | 0.333333 | 3.09032 |
| SH3KBP1 | Adapter | FAC | 9 | 1 | 0 | 0.444444 | 2.51613 |
| SHC1 | Adapter | FACA | 24 | 7 | 0 | 0.264493 | 2.12903 |
| SIRPA | Receptor | FACA | 4 | 2 | 0 | 0.166667 | 2.90968 |
| SLC9A1 | Exchanger | FACA | 1 | 0 | 0 | 0 | 3.25806 |
| SORBS1 | Adapter | FACA | 9 | 0 | 0 | 0.277778 | 2.39355 |
| SORBS2 | Adapter | FAC | 6 | 1 | 0 | 0.333333 | 2.6 |
| SORBS3 | Cytoskeletal | FAC | 5 | 1 | 0 | 0.3 | 2.60645 |
| SOS1 | RasGEF | FACA | 13 | 1 | 2 | 0.115385 | 2.49677 |
| SRC | TyrKinase | FAC | 45 | 10 | 32 | 0.124242 | 1.92258 |
| STAT3 | TF | FAC | 7 | 6 | 0 | 0.285714 | 2.42581 |
| SYK | TyrKinase | FACA | 19 | 6 | 10 | 0.397661 | 2.10323 |
| TES | Adapter | FAC | 4 | 0 | 0 | 0.333333 | 2.95484 |
| TESK1 | DualKinase | FACA | 3 | 2 | 1 | 0 | 3.06452 |
| TGFB1I1 | Adapter | FAC | 9 | 2 | 0 | 0.222222 | 2.49677 |
| THY1 | Adhesion | FACA | 5 | 0 | 0 | 0.6 | 2.47742 |
| TIAM1 | GEF | FACA | 6 | 4 | 1 | 0.133333 | 2.43226 |
| TLN1 | Cytoskeletal | FAC | 13 | 3 | 0 | 0.192308 | 2.25161 |
| TNS1 | Cytoskeletal | FAC | 4 | 1 | 0 | 0.166667 | 2.56129 |
| TRIO | GEF | FACA | 5 | 0 | 2 | 0.1 | 2.50323 |
| TRIP6 | Adapter | FAC | 5 | 1 | 0 | 0.2 | 2.62581 |
| TRPM7 | Channel | FAC | 1 | 0 | 1 | 0 | 3.96774 |
| TSPAN1 | Adapter | FACA | 3 | 0 | 0 | 0.333333 | 2.66452 |
| VASP | ActinBinding | FAC | 13 | 3 | 0 | 0.153846 | 2.45161 |
| VAV1 | GEF | FACA | 18 | 7 | 3 | 0.27451 | 2.23871 |
| VCL | Cytoskeletal | FAC | 15 | 3 | 0 | 0.161905 | 2.25161 |
| VIL2 | Cytoskeletal | FAC | 13 | 5 | 0 | 0.128205 | 2.26452 |
| VIM | Cytoskeletal | FACA | 5 | 3 | 0 | 0 | 2.68387 |
| ZYX | Cytoskeletal | FAC | 9 | 0 | 0 | 0.111111 | 2.67097 |
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