Focal Adhesion Network Components

VCL

Swiss-Prot Human Accession Code: P18206
List of interactions:

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. J. A. Wilkins, S. Lin, Cell. 28, 83 (1982). PubMed ID: 6802502

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. P. R. Bois, R. A. Borgon, C. Vonrhein, et al., Mol. Cell. Biol. 25, 6112 (2005). PubMed ID: 15988023

Source:ARPC2Type of molecule:ActinBinding Location:FACA
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. K. A. DeMali, C. A. Barlow, K. Burridge, J. Cell. Biol. 159, 881 (2002). PubMed ID: 12473693

Source:CAPN1Type of molecule:CysProtease Location:FACA
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. K. Serrano, D. V. Devine, Cell. Motil. Cytoskeleton. 58, 242 (2004). PubMed ID: 15236355

Source:TGFB1I1Type of molecule:Adapter Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. M. Thomas, M. Hagel, C. E. Turner, J. Cell. Sci. 112, 181 (1999). PubMed ID: 9858471

Source:PXNType of molecule:Adapter Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. C. E. Turner, J. T. Miller, J. Cell. Sci. 107, 1583 (1994). PubMed ID: 7525621

Source:PIP2Type of molecule:Lipid Location:FACA
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. A. P. Gilmore, K. Burridge, Nature. 381, 531 (1996). PubMed ID: 8632828

Source:PRKCAType of molecule:SerThrKinase Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Activation Effect:+
References:
1. W. H. Ziegler, U. Tigges, A. Zieseniss, et al., J. Biol. Chem. 277, 7396 (2002). PubMed ID: 11741957

Source:PKD1Type of molecule:Channel Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. L. Geng, C. R. Burrow, H. P. Li, et al., Biochim. Biophys. Acta. 1535, 21 (2001). PubMed ID: 11113628

Source:SORBS1Type of molecule:Adapter Location:FACA
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Zhang, J. Liu, A. Cheng, et al., EMBO. J. 25, 5284 (2006). PubMed ID: 17082770

Source:RAVER1Type of molecule:RNAMetabolism Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Huttelmaier, S. Illenberger, I. Grosheva, et al., J. Cell. Biol. 155, 775 (2001). PubMed ID: 11724819

Source:DMNType of molecule:Adapter Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. R. M. Bellin, T. W. Huiatt, D. R. Critchley, et al., J. Biol. Chem. 276, 32330 (2001). PubMed ID: 11418616

Source:TLN1Type of molecule:Cytoskeletal Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. P. Jones, P. Jackson, G. J. Price, et al., J. Cell. Biol. 109, 2917 (1990). PubMed ID: 2512301

Source:VASPType of molecule:ActinBinding Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Reinhard, M. Rudiger, B. M. Jockusch, et al., FEBS. Lett. 399, 103 (1997). PubMed ID: 8980130

Source:VCLType of molecule:Cytoskeletal Location:FAC
Target:SORBS3Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. N. Kioka, S. Sakata, T. Kawauchi, et al., J. Cell. Biol. 144, 59 (1999). PubMed ID: 9885244