Focal Adhesion Network Components

TRIO

Swiss-Prot Human Accession Code: O75962
List of interactions:

Source:PTK2Type of molecule:TyrKinase Location:FAC
Target:TRIOType of molecule:GEF Location:FACA
Type of interaction:Binding Effect:0
References:
1. Q. G. Medley, E. G. Buchbinder, K. Tachibana, et al., J. Biol. Chem. 278, 13265 (2003). PubMed ID: 12551902

Source:FLNAType of molecule:ActinBinding Location:FAC
Target:TRIOType of molecule:GEF Location:FACA
Type of interaction:Binding Effect:0
References:
1. J. M. Bellanger, C. Astier, C. Sardet, et al., Nat. Cell. Biol. 2, 888 (2001). PubMed ID: 11146652

Source:PTPRFType of molecule:TyrPhosphatase Location:FAC
Target:TRIOType of molecule:GEF Location:FACA
Type of interaction:Binding Effect:0
References:
1. A. Debant, C. Serra-Pages, K. Seipel, et al., Proc. Natl. Acad. Sci. U. S. A. 93, 5466 (1996). PubMed ID: 8643598

Source:TRIOType of molecule:GEF Location:FACA
Target:RAC1Type of molecule:GTPase Location:FACA
Type of interaction:Activation Effect:+
References:
1. J. M. Bellanger, J. B. Lazaro, S. Diriong, et al., Oncogene. 16, 147 (1998). PubMed ID: 9464532

Source:TRIOType of molecule:GEF Location:FACA
Target:RHOAType of molecule:GTPase Location:FACA
Type of interaction:Activation Effect:+
References:
1. J. M. Bellanger, J. B. Lazaro, S. Diriong, et al., Oncogene. 16, 147 (1998). PubMed ID: 9464532