Focal Adhesion Network Components

STAT3

Swiss-Prot Human Accession Code: P40763
List of interactions:

Source:MAPK8Type of molecule:SerThrKinase Location:FACA
Target:STAT3Type of molecule:TF Location:FAC
Type of interaction:Activation Effect:+
References:
1. C. P. Lim, X. Cao, J. Biol. Chem. 274, 31055 (1999). PubMed ID: 10521505

Source:PRKCAType of molecule:SerThrKinase Location:FAC
Target:STAT3Type of molecule:TF Location:FAC
Type of interaction:Activation Effect:+
References:
1. N. Jain, T. Zhang, W. H. Kee, et al., J. Biol. Chem. 274, 24392 (1999). PubMed ID: 10446219

Source:RAC1Type of molecule:GTPase Location:FACA
Target:STAT3Type of molecule:TF Location:FAC
Type of interaction:Binding Effect:0
References:
1. A. R. Simon, H. G. Vikis, S. Stewart, et al., Science. 290, 144 (2000). PubMed ID: 11021801

Source:PTPN11Type of molecule:TyrPhosphatase Location:FAC
Target:STAT3Type of molecule:TF Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. H. Kim, H. Baumann, Mol. Cell. Biol. 19, 5326 (1999). PubMed ID: 10409724

Source:SRCType of molecule:TyrKinase Location:FAC
Target:STAT3Type of molecule:TF Location:FAC
Type of interaction:Activation Effect:+
References:
1. X. Cao, A. Tay, G. R. Guy, et al., Mol. Cell. Biol. 16, 1595 (1996). PubMed ID: 8657134

Source:SYKType of molecule:TyrKinase Location:FACA
Target:STAT3Type of molecule:TF Location:FAC
Type of interaction:Activation Effect:+
References:
1. L. Su, M. David, J. Biol. Chem. 275, 12661 (2000). PubMed ID: 10777558

Source:PTPN2Type of molecule:TyrPhosphatase Location:FACA
Target:STAT3Type of molecule:TF Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. T. Yamamoto, Y. Sekine, K. Kashima, et al., Biochem. Biophys. Res. Commun. 297, 811 (2002). PubMed ID: 12359225