Focal Adhesion Network Components

ROCK1

Swiss-Prot Human Accession Code: Q13464
List of interactions:

Source:FLNAType of molecule:ActinBinding Location:FAC
Target:ROCK1Type of molecule:SerThrKinase Location:FACA
Type of interaction:Binding Effect:0
References:
1. K. Ueda, Y. Ohta, H. Hosoya, Biochem. Biophys. Res. Commun. 301, 886 (2003). PubMed ID: 12589795

Source:RHOAType of molecule:GTPase Location:FACA
Target:ROCK1Type of molecule:SerThrKinase Location:FACA
Type of interaction:Activation Effect:+
References:
1. K. Fujisawa, A. Fujita, T. Ishizaki, et al., J. Biol. Chem. 271, 23022 (1996). PubMed ID: 8798490

Source:ROCK1Type of molecule:SerThrKinase Location:FACA
Target:VIL2Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Activation Effect:+
References:
1. N. Oshiro, Y. Fukata, K. Kaibuchi, J. Biol. Chem. 273, 34663 (1999). PubMed ID: 9856983

Source:ROCK1Type of molecule:SerThrKinase Location:FACA
Target:LIMK1Type of molecule:SerThrKinase Location:FACA
Type of interaction:Activation Effect:+
References:
1. K. Ohashi, K. Nagata, M. Maekawa, et al., J. Biol. Chem. 275, 3577 (2000). PubMed ID: 10652353

Source:ROCK1Type of molecule:SerThrKinase Location:FACA
Target:PTENType of molecule:PtdInsPhosphatase Location:FACA
Type of interaction:Activation Effect:+
References:
1. Z. Li, X. Dong, Z. Wang, et al., Nat. Cell. Biol. 7, 399 (2005). PubMed ID: 15793569

Source:ROCK1Type of molecule:SerThrKinase Location:FACA
Target:VIMType of molecule:Cytoskeletal Location:FACA
Type of interaction:Activation Effect:+
References:
1. H. Goto, H. Kosako, K. Tanabe, et al., J. Biol. Chem. 273, 11728 (1998). PubMed ID: 9565595