Focal Adhesion Network Components

RICS

Swiss-Prot Human Accession Code: Q86YL6
List of interactions:

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:RICSType of molecule:GAP Location:FACA
Type of interaction:Binding Effect:0
References:
1. S. Y. Moon, H. Zang, Y. Zheng, J. Biol. Chem. 278, 4151 (2003). PubMed ID: 12454018

Source:CRKLType of molecule:Adapter Location:FAC
Target:RICSType of molecule:GAP Location:FACA
Type of interaction:Binding Effect:0
References:
1. T. Nakamura, M. Komiya, K. Sone, et al., Mol. Cell. Biol. 22, 8721 (2002). PubMed ID: 12446789

Source:FYNType of molecule:TyrKinase Location:FACA
Target:RICSType of molecule:GAP Location:FACA
Type of interaction:Activation Effect:+
References:
1. S. Taniguchi, H. Liu, T. Nakazawa, et al., Biochem. Biophys. Res. Commun. 306, 151 (2003). PubMed ID: 12788081

Source:GAB1Type of molecule:Adaptor Location:FAC
Target:RICSType of molecule:GAP Location:FACA
Type of interaction:Binding Effect:0
References:
1. C. Zhao, H. Ma, E. Bossy-Wetzel, et al., J. Biol. Chem. 278, 34641 (2003). PubMed ID: 12819203

Source:PLCG1Type of molecule:PtdInsKinase Location:FAC
Target:RICSType of molecule:GAP Location:FACA
Type of interaction:Binding Effect:0
References:
1. S. Y. Moon, H. Zang, Y. Zheng, J. Biol. Chem. 278, 4151 (2003). PubMed ID: 12454018

Source:RICSType of molecule:GAP Location:FACA
Target:RAC1Type of molecule:GTPase Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. S. Y. Moon, H. Zang, Y. Zheng, J. Biol. Chem. 278, 4151 (2003). PubMed ID: 12454018

Source:RICSType of molecule:GAP Location:FACA
Target:RHOAType of molecule:GTPase Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. S. Y. Moon, H. Zang, Y. Zheng, J. Biol. Chem. 278, 4151 (2003). PubMed ID: 12454018

Source:SRCType of molecule:TyrKinase Location:FAC
Target:RICSType of molecule:GAP Location:FACA
Type of interaction:Activation Effect:+
References:
1. S. Y. Moon, H. Zang, Y. Zheng, J. Biol. Chem. 278, 4151 (2003). PubMed ID: 12454018