Focal Adhesion Network Components

PTPRA

Swiss-Prot Human Accession Code: P18433
List of interactions:

Source:GRB2Type of molecule:Adapter Location:FAC
Target:PTPRAType of molecule:TyrPhosphatase Location:FAC
Type of interaction:Binding Effect:0
References:
1. EMBO. J. 13, 3020 (1994). PubMed ID: 7518772

Source:PIK3CAType of molecule:PtdInsKinase Location:FACA
Target:PTPRAType of molecule:TyrPhosphatase Location:FAC
Type of interaction:Binding Effect:0
References:
1. A. Stetak, P. Csermely, A. Ullrich, et al., Biochem. Biophys. Res. Commun. 288, 564 (2001). PubMed ID: 11676480

Source:PRKCAType of molecule:SerThrKinase Location:FAC
Target:PTPRAType of molecule:TyrPhosphatase Location:FAC
Type of interaction:Activation Effect:+
References:
1. D. T. Brandt, A. Goerke, M. Heuer, et al., et al., J. Biol. Chem. 278, 34073 (2003). PubMed ID: 12826681

Source:PTPRAType of molecule:TyrPhosphatase Location:FAC
Target:BCAR1Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. Q. Hao, S. A. Rutherford, B. Low, et al., Free. Radic. Biol. Med. 41, 302 (2006). PubMed ID: 16814111

Source:PTPRAType of molecule:TyrPhosphatase Location:FAC
Target:FYNType of molecule:TyrKinase Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. et al., J. Cell. Biol. 161, 143 (2003). PubMed ID: 12682088

Source:PTPRAType of molecule:TyrPhosphatase Location:FAC
Target:SRCType of molecule:TyrKinase Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. et al., EMBO. J. 12, 3789 (1993). PubMed ID: 7691597

Source:SRCType of molecule:TyrKinase Location:FAC
Target:PTPRAType of molecule:TyrPhosphatase Location:FAC
Type of interaction:Activation Effect:+
References:
1. EMBO. J. 13, 3020 (1994). PubMed ID: 7518772