Focal Adhesion Network Components

PTPN2

Swiss-Prot Human Accession Code: P17706
List of interactions:

Source:ITGA5Type of molecule:Adhesion Location:FAC
Target:PTPN2Type of molecule:TyrPhosphatase Location:FACA
Type of interaction:Activation Effect:+
References:
1. E. Mattila, T. Pellinen, J. Nevo, et al., Nat. Cell. Biol. 7, 78 (2005). PubMed ID: 15592458

Source:PTPN2Type of molecule:TyrPhosphatase Location:FACA
Target:SRCType of molecule:TyrKinase Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. et al., Nat. Immunol. 6, 253 (2005). PubMed ID: 15696169

Source:PTPN2Type of molecule:TyrPhosphatase Location:FACA
Target:STAT3Type of molecule:TF Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. T. Yamamoto, Y. Sekine, K. Kashima, et al., Biochem. Biophys. Res. Commun. 297, 811 (2002). PubMed ID: 12359225

Source:PTPN2Type of molecule:TyrPhosphatase Location:FACA
Target:SHC1Type of molecule:Adapter Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. T. Tiganis, A. M. Bennett, K. S. Ravichandran, et al., Mol. Cell. Biol. 18, 1622 (1998). PubMed ID: 9488479