Focal Adhesion Network Components

PRKACA

Swiss-Prot Human Accession Code: P17612
List of interactions:

Source:PRKACAType of molecule:SerThrKinase Location:FACA
Target:CAPN1Type of molecule:CysProtease Location:FACA
Type of interaction:Activation Effect:+
References:
1. H. Shiraha, A. Glading, J. Chou, et al., Mol. Cell. Biol. 22, 2716 (2002). PubMed ID: 11909964

Source:PRKACAType of molecule:SerThrKinase Location:FACA
Target:CSKType of molecule:TyrKinase Location:FAC
Type of interaction:Activation Effect:+
References:
1. G. Sun, S. Ke, R. J. Budde, Arch. Biochem. Biophys. 343, 194 (1997). PubMed ID: 9224730

Source:PRKACAType of molecule:SerThrKinase Location:FACA
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Activation Effect:+
References:
1. S. L. Jones, J. Leukoc. Biol. 71, 1042 (2002). PubMed ID: 12050191

Source:PRKACAType of molecule:SerThrKinase Location:FACA
Target:LASP1Type of molecule:ActinBinding Location:FAC
Type of interaction:Activation Effect:+
References:
1. C. Keicher, S. Gambaryan, E. Schulze, et al., Biochem. Biophys. Res. Commun. 324, 308 (2004). PubMed ID: 15465019

Source:PRKACAType of molecule:SerThrKinase Location:FACA
Target:PTPN12Type of molecule:TyrPhosphatase Location:FAC
Type of interaction:Activation Effect:+
References:
1. A. J. Garton, N. K. Tonks, EMBO. J. 13, 3763 (1994). PubMed ID: 7520867

Source:PRKACAType of molecule:SerThrKinase Location:FACA
Target:RHOAType of molecule:GTPase Location:FACA
Type of interaction:Activation Effect:+
References:
1. P. Lang, F. Gesbert, M. Delespine-Carmagnat, et al., EMBO. J. 15, 510 (1996). PubMed ID: 8599934

Source:PRKACAType of molecule:SerThrKinase Location:FACA
Target:SRCType of molecule:TyrKinase Location:FAC
Type of interaction:Activation Effect:+
References:
1. P. Yaciuk, J. K. Choi, D. Shalloway, Mol. Cell. Biol. 9, 2453 (1989). PubMed ID: 2474754

Source:PRKACAType of molecule:SerThrKinase Location:FACA
Target:VASPType of molecule:ActinBinding Location:FAC
Type of interaction:Activation Effect:+
References:
1. E. Butt, K. Abel, M. Krieger, et al., J. Biol. Chem. 269, 14509 (1994). PubMed ID: 8182057

Source:PRKACAType of molecule:SerThrKinase Location:FACA
Target:FLNAType of molecule:ActinBinding Location:FAC
Type of interaction:Activation Effect:+
References:
1. D. Wallach, P. J. Davies, I. Pastan, J. Biol. Chem. 253, 4739 (1978). PubMed ID: 207708