Focal Adhesion Network Components

PLD1

Swiss-Prot Human Accession Code: Q13393
List of interactions:

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:PLD1Type of molecule:Phospholipase Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. S. Lee, J. B. Park, J. H. Kim, et al., J. Biol. Chem. 276, 28252 (2001). PubMed ID: 11373276

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:PLD1Type of molecule:Phospholipase Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. J. B. Park, J. H. Kim, Y. Kim, et al., J. Biol. Chem. 275, 21295 (2000). PubMed ID: 10801846

Source:ARF1Type of molecule:GTPase Location:FACA
Target:PLD1Type of molecule:Phospholipase Location:FACA
Type of interaction:Activation Effect:+
References:
1. N. Nakamura, Y. Banno, K. Tamiya-Koizumi, Biochem. Biophys. Res. Commun. 335, 117 (2005). PubMed ID: 16054594

Source:PIP2Type of molecule:Lipid Location:FACA
Target:PLD1Type of molecule:Phospholipase Location:FACA
Type of interaction:Activation Effect:+
References:
1. M. Liscovitch, V. Chalifa, P. Pertile, et al., J. Biol. Chem. 269, 21403 (1994). PubMed ID: 8063770

Source:PRKCAType of molecule:SerThrKinase Location:FAC
Target:PLD1Type of molecule:Phospholipase Location:FACA
Type of interaction:Activation Effect:+
References:
1. K. M. Conricode, K. A. Brewer, J. H. Exton, J. Biol. Chem. 267, 7199 (1992). PubMed ID: 1559964

Source:PLD1Type of molecule:Phospholipase Location:FACA
Target:PIP5K1CType of molecule:PtdInsKinase Location:FACA
Type of interaction:Binding Effect:0
References:
1. N. Divecha, M. Roefs, J. R. Halstead, et al., EMBO. J. 19, 5440 (2000). PubMed ID: 11032811

Source:PLD1Type of molecule:Phospholipase Location:FACA
Target:DNM2Type of molecule:GTPase Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. C. S. Lee, I. S. Kim, J. B. Park, et al., Nat. Cell. Biol. 8, 477 (2006). PubMed ID: 16622417

Source:RAC1Type of molecule:GTPase Location:FACA
Target:PLD1Type of molecule:Phospholipase Location:FACA
Type of interaction:Activation Effect:+
References:
1. D. J. Powner, M. N. Hodgkin, M. J. Wakelam, Mol. Biol. Cell. 13, 1252 (2002). PubMed ID: 11950936

Source:RHOAType of molecule:GTPase Location:FACA
Target:PLD1Type of molecule:Phospholipase Location:FACA
Type of interaction:Activation Effect:+
References:
1. H. Genth, M. Schmidt, R. Gerhard, et al., Biochem. Biophys. Res. Commun. 302, 127 (2003). PubMed ID: 12593858