Focal Adhesion Network Components

PDPK1

Swiss-Prot Human Accession Code: O15530
List of interactions:

Source:PDPK1Type of molecule:SerThrKinase Location:FAC
Target:AKT1Type of molecule:SerThrKinase Location:FACA
Type of interaction:Activation Effect:+
References:
1. F. Rintelen, H. Stocker, G. Thomas, et al., Proc. Natl. Acad. Sci. U. S. A. 98, 15020 (2001). PubMed ID: 11752451

Source:PDPK1Type of molecule:SerThrKinase Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Activation Effect:+
References:
1. R. I. Kirk, M. R. Sanderson, K. M. Lerea, J. Biol. Chem. 275, 30901 (2000). PubMed ID: 10896934

Source:PDPK1Type of molecule:SerThrKinase Location:FAC
Target:PAK1Type of molecule:SerThrKinase Location:FAC
Type of interaction:Activation Effect:+
References:
1. C. C. King, E. M. Gardiner, F. T. Zenke, et al., J. Biol. Chem. 275, 41201 (2001). PubMed ID: 10995762

Source:PDPK1Type of molecule:SerThrKinase Location:FAC
Target:PRKCAType of molecule:SerThrKinase Location:FAC
Type of interaction:Activation Effect:+
References:
1. A. Balendran, G. R. Hare, A. Kieloch, et al., FEBS. Lett. 484, 217 (2000). PubMed ID: 11078882

Source:PDPK1Type of molecule:SerThrKinase Location:FAC
Target:PTK2BType of molecule:TyrKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. Y. Taniyama, D. S. Weber, P. Rocic, et al., Mol. Cell. Biol. 23, 8019 (2003). PubMed ID: 14585963

Source:SRCType of molecule:TyrKinase Location:FAC
Target:PDPK1Type of molecule:SerThrKinase Location:FAC
Type of interaction:Activation Effect:+
References:
1. Y. Taniyama, D. S. Weber, P. Rocic, et al., Mol. Cell. Biol. 23, 8019 (2003). PubMed ID: 14585963