Focal Adhesion Network Components

MAPK1

Swiss-Prot Human Accession Code: P28482
List of interactions:

Source:MAPK1Type of molecule:SerThrKinase Location:FACA
Target:CAPN1Type of molecule:CysProtease Location:FACA
Type of interaction:Activation Effect:+
References:
1. A. Glading, R. J. Bodnar, I. J. Reynolds, et al., Mol. Cell. Biol. 24, 2499 (2004). PubMed ID: 14993287

Source:MAPK1Type of molecule:SerThrKinase Location:FACA
Target:PXNType of molecule:Adapter Location:FAC
Type of interaction:Activation Effect:+
References:
1. H. Ku, K. E. Meier, J. Biol. Chem. 275, 11333 (2000). PubMed ID: 10753946

Source:MAPK1Type of molecule:SerThrKinase Location:FACA
Target:SORBS3Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Activation Effect:+
References:
1. M. Mitsushima, A. Suwa, T. Amachi, et al., J. Biol. Chem. 279, 34570 (2004). PubMed ID: 15184391

Source:MAPK1Type of molecule:SerThrKinase Location:FACA
Target:SOS1Type of molecule:RasGEF Location:FACA
Type of interaction:Activation Effect:+
References:
1. S. B. Waters, K. H. Holt, et al., J. Biol. Chem. 271, 6328 (1996). PubMed ID: 8626428

Source:MAPK1Type of molecule:SerThrKinase Location:FACA
Target:VAV1Type of molecule:GEF Location:FACA
Type of interaction:Activation Effect:+
References:
1. I. S. Lee, Y. Liu, M. Narazaki, et al., FEBS. Lett. 401, 133 (1997). PubMed ID: 9013873

Source:MAPK1Type of molecule:SerThrKinase Location:FACA
Target:PAK1Type of molecule:SerThrKinase Location:FAC
Type of interaction:Activation Effect:+
References:
1. L. J. Sundberg-Smith, J. T. Doherty, C. P. Mack, et al., J. Biol. Chem. 280, 2055 (2005). PubMed ID: 15542607

Source:MAPK1Type of molecule:SerThrKinase Location:FACA
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. N. Ahmed, J. Niu, D. J. Dorahy, et al., Oncogene. 21, 1370 (2002). PubMed ID: 11857080

Source:GIT1Type of molecule:GAP Location:FAC
Target:MAPK1Type of molecule:SerThrKinase Location:FACA
Type of interaction:Binding Effect:0
References:
1. G. Yin, Q. Zheng, C. Yan, et al., J. Biol. Chem. 280, 27705 (2005). PubMed ID: 15923189