Focal Adhesion Network Components

ITGB1

Swiss-Prot Human Accession Code: P05556
List of interactions:

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. C. A. Otey, F. M. Pavalko, K. Burridge, J. Cell. Biol. 111, 721 (1990). PubMed ID: 2116421

Source:ADAM12Type of molecule:Metalloproteinase Location:FACA
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. Z. Zhao, J. Gruszczynska-Biegala, T. Cheuvront, et al., Exp. Cell. Res. 298, 28 (2004). PubMed ID: 15242759

Source:AKT1Type of molecule:SerThrKinase Location:FACA
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Activation Effect:+
References:
1. R. I. Kirk, M. R. Sanderson, K. M. Lerea, J. Biol. Chem. 275, 30901 (2000). PubMed ID: 10896934

Source:CAPN1Type of molecule:CysProtease Location:FACA
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. X. Du, T. C. Saido, S. Tsubuki, et al., J. Biol. Chem. 270, 26146 (1995). PubMed ID: 7592818

Source:ITGB3BPType of molecule:TF Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. J. Shattil, T. O'Toole, M. Eigenthaler, et al., J. Cell. Biol. 131, 807 (1995). PubMed ID: 7593198

Source:MAPK1Type of molecule:SerThrKinase Location:FACA
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. N. Ahmed, J. Niu, D. J. Dorahy, et al., Oncogene. 21, 1370 (2002). PubMed ID: 11857080

Source:PTK2Type of molecule:TyrKinase Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. R. Bergan, E. Kyle, P. Nguyen, et al., Clin. Exp. Metastasis. 14, 389 (1996). PubMed ID: 8878413

Source:FHL2Type of molecule:Adapter Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. T. Samson, N. Smyth, S. Janetzky, et al., J. Biol. Chem. 279, 28641 (2004). PubMed ID: 15117962

Source:FLNAType of molecule:ActinBinding Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. D. A. Calderwood, A. Huttenlocher, W. B. Kiosses, et al., Nat. Cell. Biol. 3, 1060 (2002). PubMed ID: 11781567

Source:FYNType of molecule:TyrKinase Location:FACA
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Activation Effect:+
References:
1. A. Mariotti, P. A. Kedeshian, M. Dans, et al., J. Cell. Biol. 155, 447 (2001). PubMed ID: 11684709

Source:KCNH2Type of molecule:Channel Location:FACA
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. A. Arcangeli, A. Becchetti, A. Cherubini, et al., Biochem. Soc. Trans. 32, 826 (2004). PubMed ID: 15494025

Source:CD47Type of molecule:Receptor Location:FACA
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. E. Brown, L. Hooper, T. Ho, et al., J. Cell. Biol. 111, 2785 (1991). PubMed ID: 2277087

Source:ILKType of molecule:SerThrKinase Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. G. E. Hannigan, C. Leung-Hagesteijn, L. Fitz-Gibbon, et al., Nature. 379, 91 (1996). PubMed ID: 8538749

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:C20orf42Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Kloeker, M. B. Major, D. A. Calderwood, et al., J. Biol. Chem. 279, 6824 (2004). PubMed ID: 14634021

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:PXNType of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. L. M. Chen, D. Bailey, C. Fernandez-Valle, J. Neurosci. 20, 3776 (2000). PubMed ID: 10804218

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:PKD1Type of molecule:Channel Location:FAC
Type of interaction:Binding Effect:0
References:
1. P. D. Wilson, L. Geng, X. Li, et al., Lab. Invest. 79, 1311 (1999). PubMed ID: 10532593

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:PLEC1Type of molecule:Cytoskeletal Location:FACA
Type of interaction:Binding Effect:0
References:
1. D. Geerts, L. Fontao, M. G. Nievers, et al., J. Cell. Biol. 147, 417 (1999). PubMed ID: 10525545

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:PPP2CAType of molecule:SerThrPhosphatase Location:FAC
Type of interaction:Binding Effect:0
References:
1. K. Suzuki, Y. Chikamatsu, K. Takahashi, J. Cell. Physiol. 203, 487 (2005). PubMed ID: 15521075

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:PTK2BType of molecule:TyrKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. B. Butler, S. D. Blystone, J. Biol. Chem. 280, 14556 (2005). PubMed ID: 15695828

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:GNB2L1Type of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. J. Liliental, D. D. Chang, J. Biol. Chem. 273, 2379 (1998). PubMed ID: 9442085

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:SHC1Type of molecule:Adapter Location:FACA
Type of interaction:Binding Effect:0
References:
1. K. J. Cowan, D. A. Law, D. R. Phillips, J. Biol. Chem. 275, 36423 (2000). PubMed ID: 10964917

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:SYKType of molecule:TyrKinase Location:FACA
Type of interaction:Binding Effect:0
References:
1. S. Sarkar, M. M. Rooney, S. T. Lord, Biochem. J. 338, 677 (1999). PubMed ID: 10051438

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:TLN1Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Patil, A. Jedsadayanmata, J. D. Wencel-Drake, et al., J. Biol. Chem. 274, 28575 (1999). PubMed ID: 10497223

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:TNS1Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. H. Lo, Int. J. Biochem. Cell. Biol. 36, 31 (2003). PubMed ID: 14592531

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:TSPAN1Type of molecule:Adapter Location:FACA
Type of interaction:Binding Effect:0
References:
1. F. Berditchevski, E. Odintsova, J. Cell. Biol. 146, 477 (1999). PubMed ID: 10427099

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:THY1Type of molecule:Adhesion Location:FACA
Type of interaction:Binding Effect:0
References:
1. L. Leyton, P. Schneider, C. V. Labra, et al., Curr. Biol. 11, 1028 (2001). PubMed ID: 11470407

Source:ITGB1Type of molecule:Adhesion Location:FAC
Target:PLAURType of molecule:Receptor Location:FACA
Type of interaction:Binding Effect:0
References:
1. T. Tarui, N. Andronicos, R. P. Czekay, et al., J. Biol. Chem. 278, 29863 (2003). PubMed ID: 12754207

Source:PDPK1Type of molecule:SerThrKinase Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Activation Effect:+
References:
1. R. I. Kirk, M. R. Sanderson, K. M. Lerea, J. Biol. Chem. 275, 30901 (2000). PubMed ID: 10896934

Source:PRKACAType of molecule:SerThrKinase Location:FACA
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Activation Effect:+
References:
1. S. L. Jones, J. Leukoc. Biol. 71, 1042 (2002). PubMed ID: 12050191

Source:PRKCAType of molecule:SerThrKinase Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Activation Effect:+
References:
1. S. Fagerholm, N. Morrice, C. G. Gahmberg, et al., J. Biol. Chem. 277, 1728 (2002). PubMed ID: 11700305

Source:SRCType of molecule:TyrKinase Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Activation Effect:+
References:
1. A. Datta, F. Huber, D. Boettiger, J. Biol. Chem. 277, 3943 (2002). PubMed ID: 11723131