Focal Adhesion Network Components

ITGA5

Swiss-Prot Human Accession Code: P56199
List of interactions:

Source:ADAM12Type of molecule:Metalloproteinase Location:FACA
Target:ITGA5Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. Z. Zhao, J. Gruszczynska-Biegala, T. Cheuvront, et al., Exp. Cell. Res. 298, 28 (2004). PubMed ID: 15242759

Source:CALRType of molecule:Chaperone Location:FAC
Target:ITGA5Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Coppolino, C. Leung-Hagesteijn, S. Dedhar, et al., J. Biol. Chem. 270, 23132 (1995). PubMed ID: 7559457

Source:CBLType of molecule:E3ligase Location:FACA
Target:ITGA5Type of molecule:Adhesion Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. T. Zell, C. S. Warden, A. S. Chan, et al., Curr. Biol. 8, 814 (1998). PubMed ID: 9663390

Source:PTK2Type of molecule:TyrKinase Location:FAC
Target:ITGA5Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. B. P. Eliceiri, X. S. Puente, J. D. Hood, et al., J. Cell. Biol. 157, 149 (2002). PubMed ID: 11927607

Source:FHL2Type of molecule:Adapter Location:FAC
Target:ITGA5Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. T. Samson, N. Smyth, S. Janetzky, et al., J. Biol. Chem. 279, 28641 (2004). PubMed ID: 15117962

Source:CD47Type of molecule:Receptor Location:FACA
Target:ITGA5Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. E. Brown, L. Hooper, T. Ho, et al., J. Cell. Biol. 111, 2785 (1991). PubMed ID: 2277087

Source:ITGA5Type of molecule:Adhesion Location:FAC
Target:PXNType of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Liu, S. M. Thomas, D. G. Woodside, et al., Nature. 402, 676 (2000). PubMed ID: 10604475

Source:ITGA5Type of molecule:Adhesion Location:FAC
Target:PKD1Type of molecule:Channel Location:FAC
Type of interaction:Binding Effect:0
References:
1. P. D. Wilson, L. Geng, X. Li, et al., Lab. Invest. 79, 1311 (1999). PubMed ID: 10532593

Source:ITGA5Type of molecule:Adhesion Location:FAC
Target:TLN1Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. K. L. Wegener, A. W. Partridge, J. Han, et al., Cell. 128, 171 (2007). PubMed ID: 17218263

Source:ITGA5Type of molecule:Adhesion Location:FAC
Target:PTPN2Type of molecule:TyrPhosphatase Location:FACA
Type of interaction:Activation Effect:+
References:
1. E. Mattila, T. Pellinen, J. Nevo, et al., Nat. Cell. Biol. 7, 78 (2005). PubMed ID: 15592458

Source:ITGA5Type of molecule:Adhesion Location:FAC
Target:TSPAN1Type of molecule:Adapter Location:FACA
Type of interaction:Binding Effect:0
References:
1. F. Berditchevski, E. Odintsova, J. Cell. Biol. 146, 477 (1999). PubMed ID: 10427099

Source:ITGA5Type of molecule:Adhesion Location:FAC
Target:THY1Type of molecule:Adhesion Location:FACA
Type of interaction:Binding Effect:0
References:
1. A. Saalbach, A. Wetzel, U. F. Haustein, et al., Oncogene. 24, 4710 (2005). PubMed ID: 15897908

Source:ITGA5Type of molecule:Adhesion Location:FAC
Target:PLAURType of molecule:Receptor Location:FACA
Type of interaction:Binding Effect:0
References:
1. G. C. Gellert, R. H. Goldfarb, R. P. Kitson, Biochem. Biophys. Res. Commun. 315, 1025 (2004). PubMed ID: 14985115