Focal Adhesion Network Components

INPPL1

Swiss-Prot Human Accession Code: O15357
List of interactions:

Source:ABL1Type of molecule:TyrKinase Location:FAC
Target:INPPL1Type of molecule:PtdInsPhosphatase Location:FAC
Type of interaction:Binding Effect:0
References:
1. D. Wisniewski, A. Strife, S. Swendeman, et al., Blood. 93, 2707 (1999). PubMed ID: 10194451

Source:CBLType of molecule:E3ligase Location:FACA
Target:INPPL1Type of molecule:PtdInsPhosphatase Location:FAC
Type of interaction:Binding Effect:0
References:
1. I. Vandenbroere, N. Paternotte, J. E. Dumont, et al., Biochem. Biophys. Res. Commun. 300, 494 (2002). PubMed ID: 12504111

Source:FLNAType of molecule:ActinBinding Location:FAC
Target:INPPL1Type of molecule:PtdInsPhosphatase Location:FAC
Type of interaction:Binding Effect:0
References:
1. Y. Wang, R. J. Keogh, M. G. Hunter, et al., J. Immunol. 173, 6820 (2004). PubMed ID: 15557176

Source:SORBS1Type of molecule:Adapter Location:FACA
Target:INPPL1Type of molecule:PtdInsPhosphatase Location:FAC
Type of interaction:Binding Effect:0
References:
1. I. Vandenbroere, N. Paternotte, J. E. Dumont, et al., Biochem. Biophys. Res. Commun. 300, 494 (2002). PubMed ID: 12504111

Source:INPPL1Type of molecule:PtdInsPhosphatase Location:FAC
Target:PIP3Type of molecule:Lipid Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. X. Pesesse, C. Moreau, A. L. Drayer, et al., FEBS. Lett. 437, 301 (1998). PubMed ID: 9824312

Source:SRCType of molecule:TyrKinase Location:FAC
Target:INPPL1Type of molecule:PtdInsPhosphatase Location:FAC
Type of interaction:Activation Effect:+
References:
1. N. Prasad, R. S. Topping, S. J. Decker, J. Cell. Sci. 115, 3807 (2002). PubMed ID: 12235291

Source:SORBS3Type of molecule:Cytoskeletal Location:FAC
Target:INPPL1Type of molecule:PtdInsPhosphatase Location:FAC
Type of interaction:Binding Effect:0
References:
1. N. Paternotte, J. Zhang, I. Vandenbroere, et al., FEBS. J. 272, 6052 (2005). PubMed ID: 16302969