Focal Adhesion Network Components

ILK

Swiss-Prot Human Accession Code: Q13418
List of interactions:

Source:AKT1Type of molecule:SerThrKinase Location:FACA
Target:ILKType of molecule:SerThrKinase Location:FAC
Type of interaction:Activation Effect:+
References:
1. M. Delcommenne, C. Tan, V. Gray, et al., Proc. Natl. Acad. Sci. U. S. A. 95, 11211 (1998). PubMed ID: 9736715

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:ILKType of molecule:SerThrKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. A. Meyer, et al., Biochemistry. 44, 932 (2005). PubMed ID: 15654749

Source:ILKType of molecule:SerThrKinase Location:FAC
Target:AKT1Type of molecule:SerThrKinase Location:FACA
Type of interaction:Activation Effect:+
References:
1. M. Delcommenne, C. Tan, V. Gray, et al., Proc. Natl. Acad. Sci. U. S. A. 95, 11211 (1998). PubMed ID: 9736715

Source:ILKType of molecule:SerThrKinase Location:FAC
Target:ILKAPType of molecule:SerThrPhosphatase Location:FACA
Type of interaction:Binding Effect:0
References:
1. C. Leung-Hagesteijn, A. Mahendra, I. Naruszewicz, et al., EMBO. J. 20, 2160 (2001). PubMed ID: 11331582

Source:ILKType of molecule:SerThrKinase Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. G. E. Hannigan, C. Leung-Hagesteijn, L. Fitz-Gibbon, et al., Nature. 379, 91 (1996). PubMed ID: 8538749

Source:ILKType of molecule:SerThrKinase Location:FAC
Target:PARVAType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. N. Nikolopoulos, C. E. Turner, J. Biol. Chem. 277, 1568 (2002). PubMed ID: 11694518

Source:ILKType of molecule:SerThrKinase Location:FAC
Target:PARVBType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Yamaji, A. Suzuki, Y. Sugiyama, et al., J. Cell. Biol. 153, 1251 (2001). PubMed ID: 11402068

Source:ILKType of molecule:SerThrKinase Location:FAC
Target:LIMS1Type of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. Y. Tu, F. Li, S. Goicoechea, et al., Mol. Cell. Biol. 19, 2425 (1999). PubMed ID: 10022929

Source:PXNType of molecule:Adapter Location:FAC
Target:ILKType of molecule:SerThrKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. N. Nikolopoulos, C. E. Turner, J. Biol. Chem. 276, 23499 (2001). PubMed ID: 11304546

Source:PIP3Type of molecule:Lipid Location:FACA
Target:ILKType of molecule:SerThrKinase Location:FAC
Type of interaction:Activation Effect:+
References:
1. S. Dedhar, Curr. Opin. Cell. Biol. 12, 250 (2000). PubMed ID: 10712922