Focal Adhesion Network Components

GAB1

Swiss-Prot Human Accession Code: Q13480
List of interactions:

Source:GAB1Type of molecule:Adaptor Location:FAC
Target:PXNType of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. Y. Ren, S. Meng, L. Mei, et al., J. Biol. Chem. 279, 8497 (2004). PubMed ID: 14665621

Source:GAB1Type of molecule:Adaptor Location:FAC
Target:CRKType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Garcia-Guzman, F. Dolfi, K. Zeh, et al., Oncogene. 18, 7775 (2000). PubMed ID: 10618718

Source:GAB1Type of molecule:Adaptor Location:FAC
Target:GRB2Type of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Holgado-Madruga, D. R. Emlet, D. K. Moscatello, et al., Nature. 379, 560 (1996). PubMed ID: 8596638

Source:GAB1Type of molecule:Adaptor Location:FAC
Target:PIK3CAType of molecule:PtdInsKinase Location:FACA
Type of interaction:Binding Effect:0
References:
1. C. Lecoq-Lafon, F. Verdier, S. Fichelson, et al., Blood. 93, 2578 (1999). PubMed ID: 10194437

Source:GAB1Type of molecule:Adaptor Location:FAC
Target:CRKLType of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. D. Sakkab, M. Lewitzky, G. Posern, et al., J. Biol. Chem. 275, 10772 (2000). PubMed ID: 10753869

Source:GAB1Type of molecule:Adaptor Location:FAC
Target:RICSType of molecule:GAP Location:FACA
Type of interaction:Binding Effect:0
References:
1. C. Zhao, H. Ma, E. Bossy-Wetzel, et al., J. Biol. Chem. 278, 34641 (2003). PubMed ID: 12819203

Source:INSRType of molecule:Receptor Location:FACA
Target:GAB1Type of molecule:Adaptor Location:FAC
Type of interaction:Activation Effect:+
References:
1. S. Lehr, J. Kotzka, A. Herkner, et al., Biochemistry. 39, 10898 (2000). PubMed ID: 10978177

Source:PTPN11Type of molecule:TyrPhosphatase Location:FAC
Target:GAB1Type of molecule:Adaptor Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. C. Lecoq-Lafon, F. Verdier, S. Fichelson, et al., Blood. 93, 2578 (1999). PubMed ID: 10194437