Focal Adhesion Network Components

DNM2

Swiss-Prot Human Accession Code: P50570
List of interactions:

Source:SORBS2Type of molecule:Adapter Location:FAC
Target:DNM2Type of molecule:GTPase Location:FAC
Type of interaction:Binding Effect:0
References:
1. G. Cestra, D. Toomre, S. Chang, et al., Proc. Natl. Acad. Sci. U. S. A. 102, 1731 (2005). PubMed ID: 15659545

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:DNM2Type of molecule:GTPase Location:FAC
Type of interaction:Binding Effect:0
References:
1. Q. Yao, J. Chen, H. Cao, et al., J. Mol. Biol. 348, 491 (2005). PubMed ID: 15811383

Source:CBLType of molecule:E3ligase Location:FACA
Target:DNM2Type of molecule:GTPase Location:FAC
Type of interaction:Binding Effect:0
References:
1. A. Bruzzaniti, L. Neff, A. Sanjay, et al., Mol. Biol. Cell. 16, 3301 (2005). PubMed ID: 15872089

Source:CTTNType of molecule:Actinbinding Location:FAC
Target:DNM2Type of molecule:GTPase Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. A. McNiven, L. Kim, E. W. Krueger, et al., J. Cell. Biol. 151, 187 (2000). PubMed ID: 11018064

Source:DNM2Type of molecule:GTPase Location:FAC
Target:PTK2Type of molecule:TyrKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Kharbanda, A. Saleem, Z. Yuan, et al., Proc. Natl. Acad. Sci. U. S. A. 92, 6132 (1995). PubMed ID: 7597091

Source:DNM2Type of molecule:GTPase Location:FAC
Target:GRB2Type of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. A. Ando, K. Yonezawa, I. Gout, et al., EMBO. J. 13, 3033 (1994). PubMed ID: 8039498

Source:DNM2Type of molecule:GTPase Location:FAC
Target:NCK2Type of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. L. Wunderlich, A. Farago, L. Buday, Cell. Signal. 11, 25 (1999). PubMed ID: 10206341

Source:DNM2Type of molecule:GTPase Location:FAC
Target:PLCG1Type of molecule:PtdInsKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. R. Scaife, I. Gout, M. D. Waterfield, et al., EMBO. J. 13, 2574 (1994). PubMed ID: 8013457

Source:DNM2Type of molecule:GTPase Location:FAC
Target:PFN1Type of molecule:ActinBinding Location:FACA
Type of interaction:Binding Effect:0
References:
1. PubMed ID: 16319076

Source:DNM2Type of molecule:GTPase Location:FAC
Target:SDC4Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. J. Yoo, M. J. Jeong, H. J. Cho, et al., Biochem. Biophys. Res. Commun. 328, 424 (2005). PubMed ID: 15694365

Source:DNM2Type of molecule:GTPase Location:FAC
Target:KALPHA1Type of molecule:Cytoskeletal Location:FACA
Type of interaction:Binding Effect:0
References:
1. H. M. Thompson, H. Cao, J. Chen, et al., Nat. Cell. Biol. 6, 335 (2004). PubMed ID: 15048127

Source:DNM2Type of molecule:GTPase Location:FAC
Target:VAV1Type of molecule:GEF Location:FACA
Type of interaction:Binding Effect:0
References:
1. T. S. Gomez, M. J. Hamann, S. McCarney, et al., Nat. Immunol. 6, 261 (2005). PubMed ID: 15696170

Source:PLD1Type of molecule:Phospholipase Location:FACA
Target:DNM2Type of molecule:GTPase Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. C. S. Lee, I. S. Kim, J. B. Park, et al., Nat. Cell. Biol. 8, 477 (2006). PubMed ID: 16622417