Focal Adhesion Network Components

DDEF1

Swiss-Prot Human Accession Code: Q9ULH1
List of interactions:

Source:DDEF1Type of molecule:GAP Location:FAC
Target:ARF1Type of molecule:GTPase Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. C. Furman, S. M. Short, R. R. Subramanian, et al., J. Biol. Chem. 277, 7962 (2002). PubMed ID: 11773070

Source:DDEF1Type of molecule:GAP Location:FAC
Target:CTTNType of molecule:Actinbinding Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Hashimoto, M. Hirose, A. Hashimoto, et al., Proc. Natl. Acad. Sci. U. S. A. 103, 7036 (2006). PubMed ID: 16636290

Source:DDEF1Type of molecule:GAP Location:FAC
Target:PTK2Type of molecule:TyrKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. Y. Liu, J. C. Loijens, K. H. Martin, et al., Mol. Biol. Cell. 13, 2147 (2002). PubMed ID: 12058076

Source:DDEF1Type of molecule:GAP Location:FAC
Target:PXNType of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. T. Oshiro, S. Koyama, S. Sugiyama, et al., J. Biol. Chem. 277, 38618 (2002). PubMed ID: 12149250

Source:SH3KBP1Type of molecule:Adapter Location:FAC
Target:DDEF1Type of molecule:GAP Location:FAC
Type of interaction:Binding Effect:0
References:
1. K. Kowanetz, K. Husnjak, D. Holler, et al., Mol. Biol. Cell. 15, 3155 (2004). PubMed ID: 15090612

Source:PIP2Type of molecule:Lipid Location:FACA
Target:DDEF1Type of molecule:GAP Location:FAC
Type of interaction:Activation Effect:+
References:
1. M. T. Brown, J. Andrade, H. Radhakrishna, et al., Mol. Cell. Biol. 18, 7038 (1998). PubMed ID: 9819391

Source:PTK2BType of molecule:TyrKinase Location:FAC
Target:DDEF1Type of molecule:GAP Location:FAC
Type of interaction:Activation Effect:+
References:
1. A. Kruljac-Letunic, J. Moelleken, A. Kallin, et al., J. Biol. Chem. 278, 29560 (2003). PubMed ID: 12771146

Source:SRCType of molecule:TyrKinase Location:FAC
Target:DDEF1Type of molecule:GAP Location:FAC
Type of interaction:Activation Effect:+
References:
1. M. T. Brown, J. Andrade, H. Radhakrishna, et al., Mol. Cell. Biol. 18, 7038 (1998). PubMed ID: 9819391