Focal Adhesion Network Components

CRK

Swiss-Prot Human Accession Code: P46108
List of interactions:

Source:ABL1Type of molecule:TyrKinase Location:FAC
Target:CRKType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. R. Ren, Z. S. Ye, D. Baltimore, Genes. Dev. 8, 783 (1994). PubMed ID: 7926767

Source:RAPGEF1Type of molecule:GEF Location:FACA
Target:CRKType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Tanaka, T. Morishita, Y. Hashimoto, et al., Proc. Natl. Acad. Sci. U. S. A. 91, 3443 (1994). PubMed ID: 7512734

Source:BCAR1Type of molecule:Cytoskeletal Location:FAC
Target:CRKType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. R. Sakai, A. Iwamatsu, N. Hirano, et al., EMBO. J. 13, 3748 (1994). PubMed ID: 8070403

Source:CBLType of molecule:E3ligase Location:FACA
Target:CRKType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. V. Ribon, S. Hubbell, R. Herrera, et al., Mol. Cell. Biol. 16, 45 (1996). PubMed ID: 8524328

Source:CTTNType of molecule:Actinbinding Location:FAC
Target:CRKType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. L. Bougneres, S. E. Girardin, S. A. Weed, et al., J. Cell. Biol. 166, 225 (2004). PubMed ID: 15263018

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:DOCK1Type of molecule:GEF Location:FAC
Type of interaction:Binding Effect:0
References:
1. E. Kiyokawa, Y. Hashimoto, S. Kobayashi, et al., Genes. Dev. 12, 3331 (1998). PubMed ID: 9808620

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:ELMO1Type of molecule:GEF Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Akakura, B. Kar, S. Singh, et al., J. Cell. Physiol. 204, 344 (2005). PubMed ID: 15700267

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:GRB2Type of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. R. Ren, Z. S. Ye, D. Baltimore, Genes. Dev. 8, 783 (1994). PubMed ID: 7926767

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:NEDD9Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. A. J. Hunter, Y. Shimizu, J. Immunol. 159, 4806 (1997). PubMed ID: 9366405

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:MAPK8Type of molecule:SerThrKinase Location:FACA
Type of interaction:Binding Effect:0
References:
1. S. E. Girardin, M. Yaniv, EMBO. J. 20, 3437 (2001). PubMed ID: 11432831

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:PXNType of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. D. Schaller, J. T. Parsons, Mol. Cell. Biol. 15, 2635 (1995). PubMed ID: 7537852

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:RICSType of molecule:GAP Location:FACA
Type of interaction:Binding Effect:0
References:
1. S. Y. Moon, H. Zang, Y. Zheng, J. Biol. Chem. 278, 4151 (2003). PubMed ID: 12454018

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:SHC1Type of molecule:Adapter Location:FACA
Type of interaction:Binding Effect:0
References:
1. M. Matsuda, S. Ota, R. Tanimura, et al., J. Biol. Chem. 271, 14468 (1996). PubMed ID: 8662907

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:SOS1Type of molecule:RasGEF Location:FACA
Type of interaction:Binding Effect:0
References:
1. S. Okada, J. E. Pessin, J. Biol. Chem. 271, 25533 (1996). PubMed ID: 8810325

Source:CRKType of molecule:Cytoskeletal Location:FAC
Target:VAV1Type of molecule:GEF Location:FACA
Type of interaction:Binding Effect:0
References:
1. L. Smit, d. e. r. van, G. Horst, et al., J. Biol. Chem. 271, 8564 (1996). PubMed ID: 8621483

Source:GAB1Type of molecule:Adaptor Location:FAC
Target:CRKType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Garcia-Guzman, F. Dolfi, K. Zeh, et al., Oncogene. 18, 7775 (2000). PubMed ID: 10618718

Source:RAC1Type of molecule:GTPase Location:FACA
Target:CRKType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. t. e. n. PB,, J. P. Klooster, et al., J. Biol. Chem. 278, 39166 (2003). PubMed ID: 12874273