Focal Adhesion Network Components

CFL1

Swiss-Prot Human Accession Code: P23528
List of interactions:

Source:CFL1Type of molecule:ActinBinding Location:FACA
Target:ACTBType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. R. Nagaoka, H. Abe, T. Obinata, Cell. Motil. Cytoskeleton. 35, 200 (1997). PubMed ID: 8913641

Source:LIMK1Type of molecule:SerThrKinase Location:FACA
Target:CFL1Type of molecule:ActinBinding Location:FACA
Type of interaction:Activation Effect:+
References:
1. N. Yang, O. Higuchi, K. Ohashi, et al., Nature. 393, 809 (1998). PubMed ID: 9655398

Source:PPP2CAType of molecule:SerThrPhosphatase Location:FAC
Target:CFL1Type of molecule:ActinBinding Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. T. Takuma, T. Ichida, N. Yokoyama, et al., J. Biochem. (Tokyo). 120, 35 (1997). PubMed ID: 8864841

Source:TESK1Type of molecule:DualKinase Location:FACA
Target:CFL1Type of molecule:ActinBinding Location:FACA
Type of interaction:Activation Effect:+
References:
1. J. Toshima, J. Y. Toshima, T. Amano, et al., Mol. Biol. Cell. 12, 1131 (2001). PubMed ID: 11294912