Focal Adhesion Network Components

CAV1

Swiss-Prot Human Accession Code: Q03135
List of interactions:

Source:ABL1Type of molecule:TyrKinase Location:FAC
Target:CAV1Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Activation Effect:+
References:
1. A. R. Sanguinetti, C. C. Mastick, Cell. Signal. 15, 289 (2003). PubMed ID: 12531427

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:CSKType of molecule:TyrKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. H. Cao, W. E. Courchesne, C. C. Mastick, J. Biol. Chem. 277, 8771 (2002). PubMed ID: 11805080

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:DNM2Type of molecule:GTPase Location:FAC
Type of interaction:Binding Effect:0
References:
1. Q. Yao, J. Chen, H. Cao, et al., J. Mol. Biol. 348, 491 (2005). PubMed ID: 15811383

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:FLNAType of molecule:ActinBinding Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Stahlhut, Mol. Biol. Cell. 11, 325 (2000). PubMed ID: 10637311

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:GRB7Type of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. H. Lee, D. Volonte, F. Galbiati, et al., Mol. Endocrinol. 14, 1750 (2001). PubMed ID: 11075810

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:KCNH2Type of molecule:Channel Location:FACA
Type of interaction:Binding Effect:0
References:
1. A. Cherubini, G. Hofmann, S. Pillozzi, et al., Mol. Biol. Cell. 16, 2972 (2005). PubMed ID: 15800067

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:ILKType of molecule:SerThrKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. A. Meyer, et al., Biochemistry. 44, 932 (2005). PubMed ID: 15654749

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:INSRType of molecule:Receptor Location:FACA
Type of interaction:Binding Effect:0
References:
1. M. Yamamoto, Y. Toya, C. Schwencke, et al., J. Biol. Chem. 273, 26962 (1998). PubMed ID: 9756945

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:NF2Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Boyanapalli, O. B. Lahoud, L. Messiaen, et al., Biochem. Biophys. Res. Commun. 340, 1200 (2006). PubMed ID: 16405917

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:PPP2CAType of molecule:SerThrPhosphatase Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. L. Li, C. H. Ren, S. A. Tahir, et al., Mol. Cell. Biol. 23, 9389 (2003). PubMed ID: 14645548

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:PTENType of molecule:PtdInsPhosphatase Location:FACA
Type of interaction:Binding Effect:0
References:
1. A. Caselli, B. Mazzinghi, G. Camici, et al., Biochem. Biophys. Res. Commun. 296, 692 (2002). PubMed ID: 12176037

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:PTPN1Type of molecule:TyrPhosphatase Location:FACA
Type of interaction:Binding Effect:0
References:
1. A. Caselli, B. Mazzinghi, G. Camici, et al., Biochem. Biophys. Res. Commun. 296, 692 (2002). PubMed ID: 12176037

Source:CAV1Type of molecule:Cytoskeletal Location:FAC
Target:PLAURType of molecule:Receptor Location:FACA
Type of interaction:Binding Effect:0
References:
1. Y. Wei, X. Yang, Q. Liu, et al., J. Cell. Biol. 144, 1285 (1999). PubMed ID: 10087270

Source:SRCType of molecule:TyrKinase Location:FAC
Target:CAV1Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Activation Effect:+
References:
1. S. Li, J. Couet, M. P. Lisanti, J. Biol. Chem. 271, 29182 (1997). PubMed ID: 8910575