Focal Adhesion Network Components

BCAR3

Swiss-Prot Human Accession Code: O75815
List of interactions:

Source:BCAR3Type of molecule:GEF Location:FACA
Target:RAC1Type of molecule:GTPase Location:FACA
Type of interaction:Activation Effect:+
References:
1. D. Cai, A. Iyer, K. N. Felekkis, et al., Cancer. Res. 63, 6802 (2003). PubMed ID: 14583477

Source:BCAR3Type of molecule:GEF Location:FACA
Target:BCAR1Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. T. Gotoh, D. Cai, X. Tian, et al., J. Biol. Chem. 275, 30118 (2000). PubMed ID: 10896938

Source:BCAR3Type of molecule:GEF Location:FACA
Target:NEDD9Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. D. Cai, K. N. Felekkis, R. I. Near, et al., J. Immunol. 170, 969 (2003). PubMed ID: 12517963

Source:BCAR3Type of molecule:GEF Location:FACA
Target:PIK3CAType of molecule:PtdInsKinase Location:FACA
Type of interaction:Activation Effect:+
References:
1. K. N. Felekkis, R. P. Narsimhan, R. Near, et al., Mol. Cancer. Res. 3, 32 (2005). PubMed ID: 15671247

Source:BCAR3Type of molecule:GEF Location:FACA
Target:PAK1Type of molecule:SerThrKinase Location:FAC
Type of interaction:Activation Effect:+
References:
1. D. Cai, A. Iyer, K. N. Felekkis, et al., Cancer. Res. 63, 6802 (2003). PubMed ID: 14583477