Focal Adhesion Network Components

ARHGEF6

Swiss-Prot Human Accession Code: Q15052
List of interactions:

Source:ABI1Type of molecule:Adapter Location:FACA
Target:ARHGEF6Type of molecule:GEF Location:FAC
Type of interaction:Binding Effect:0
References:
1. F. Campa, N. Machuy, A. Klein, et al., Cell. Res. 16, 759 (2006). PubMed ID: 16940963

Source:CAPN1Type of molecule:CysProtease Location:FACA
Target:ARHGEF6Type of molecule:GEF Location:FAC
Type of interaction:Binding Effect:0
References:
1. G. Rosenberger, A. Gal, K. Kutsche, J. Biol. Chem. 280, 6879 (2005). PubMed ID: 15611136

Source:PTK2Type of molecule:TyrKinase Location:FAC
Target:ARHGEF6Type of molecule:GEF Location:FAC
Type of interaction:Activation Effect:+
References:
1. F. Chang, C. A. Lemmon, D. Park, et al., Mol. Biol. Cell. 18, 253 (2006). PubMed ID: 17093062

Source:GIT1Type of molecule:GAP Location:FAC
Target:ARHGEF6Type of molecule:GEF Location:FAC
Type of interaction:Binding Effect:0
References:
1. O. A. Botrugno, S. Paris, L. Za, et al., Eur. J. Cell. Biol. 85, 35 (2005). PubMed ID: 16373173

Source:PAK1Type of molecule:SerThrKinase Location:FAC
Target:ARHGEF6Type of molecule:GEF Location:FAC
Type of interaction:Binding Effect:0
References:
1. E. Manser, T. H. Loo, C. G. Koh, et al., Mol. Cell. 1, 183 (1998). PubMed ID: 9659915

Source:PARVBType of molecule:Cytoskeletal Location:FAC
Target:ARHGEF6Type of molecule:GEF Location:FAC
Type of interaction:Binding Effect:0
References:
1. G. Rosenberger, I. Jantke, A. Gal, et al., Hum. Mol. Genet. 12, 155 (2002). PubMed ID: 12499396

Source:ARHGEF6Type of molecule:GEF Location:FAC
Target:CBLType of molecule:E3ligase Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. J. A. Flanders, Q. Feng, S. Bagrodia, et al., FEBS. Lett. 550, 119 (2003). PubMed ID: 12935897

Source:ARHGEF6Type of molecule:GEF Location:FAC
Target:PPM1MType of molecule:SerThrPhosphatase Location:FAC
Type of interaction:Binding Effect:0
References:
1. C. G. Koh, E. J. Tan, E. Manser, et al., Curr. Biol. 12, 317 (2002). PubMed ID: 11864573

Source:ARHGEF6Type of molecule:GEF Location:FAC
Target:RAC1Type of molecule:GTPase Location:FACA
Type of interaction:Activation Effect:+
References:
1. et al., J. Cell. Biol. 172, 759 (2006). PubMed ID: 16492808