Focal Adhesion Network Components

ACTN1

Swiss-Prot Human Accession Code: P12814
List of interactions:

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:ACTBType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. W. Drabikowski, E. Nowak, Eur. J. Biochem. 5, 209 (1968). PubMed ID: 5667356

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:CSRP1Type of molecule:Cytoskeletal Location:FACA
Type of interaction:Binding Effect:0
References:
1. P. Pomies, H. A. Louis, M. C. Beckerle, J. Cell. Biol. 139, 157 (1998). PubMed ID: 9314536

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:ITGB1Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. C. A. Otey, F. M. Pavalko, K. Burridge, J. Cell. Biol. 111, 721 (1990). PubMed ID: 2116421

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:LPPType of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. B. Li, L. Zhuang, M. Reinhard, et al., J. Cell. Sci. 116, 1359 (2003). PubMed ID: 12615977

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:PALLDType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Ronty, A. Taivainen, M. Moza, et al., FEBS. Lett. 566, 30 (2004). PubMed ID: 15147863

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:PARVBType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Yamaji, A. Suzuki, H. Kanamori, et al., J. Cell. Biol. 165, 539 (2004). PubMed ID: 15159419

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:RAVER1Type of molecule:RNAMetabolism Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Huttelmaier, S. Illenberger, I. Grosheva, et al., J. Cell. Biol. 155, 775 (2001). PubMed ID: 11724819

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:SDC4Type of molecule:Adhesion Location:FAC
Type of interaction:Binding Effect:0
References:
1. D. K. Greene, S. Tumova, J. R. Couchman, et al., J. Biol. Chem. 278, 7617 (2003). PubMed ID: 12493766

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:TESType of molecule:Adapter Location:FAC
Type of interaction:Binding Effect:0
References:
1. B. K. Garvalov, T. E. Higgins, J. D. Sutherland, et al., J. Cell. Biol. 161, 33 (2003). PubMed ID: 12695497

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. P. R. Bois, R. A. Borgon, C. Vonrhein, et al., Mol. Cell. Biol. 25, 6112 (2005). PubMed ID: 15988023

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:ZYXType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Reinhard, J. Zumbrunn, D. Jaquemar, et al., J. Biol. Chem. 274, 13410 (1999). PubMed ID: 10224105

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:PLD1Type of molecule:Phospholipase Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. J. B. Park, J. H. Kim, Y. Kim, et al., J. Biol. Chem. 275, 21295 (2000). PubMed ID: 10801846

Source:SORBS2Type of molecule:Adapter Location:FAC
Target:ACTN1Type of molecule:Actinbundling Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Ronty, A. Taivainen, M. Moza, et al., Exp. Cell. Res. 310, 88 (2005). PubMed ID: 16125169

Source:CAPN1Type of molecule:CysProtease Location:FACA
Target:ACTN1Type of molecule:Actinbundling Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. N. Selliah, W. H. Brooks, T. L. Roszman, J. Immunol. 156, 3215 (1996). PubMed ID: 8617943

Source:PTK2Type of molecule:TyrKinase Location:FAC
Target:ACTN1Type of molecule:Actinbundling Location:FAC
Type of interaction:Activation Effect:+
References:
1. G. Izaguirre, L. Aguirre, Y. P. Hu, et al., J. Biol. Chem. 276, 28676 (2001). PubMed ID: 11369769

Source:PIP2Type of molecule:Lipid Location:FACA
Target:ACTN1Type of molecule:Actinbundling Location:FAC
Type of interaction:Activation Effect:+
References:
1. K. Fukami, T. Endo, M. Imamura, et al., J. Biol. Chem. 269, 1518 (1994). PubMed ID: 8288618

Source:PTPN1Type of molecule:TyrPhosphatase Location:FACA
Target:ACTN1Type of molecule:Actinbundling Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. Z. Zhang, S. Y. Lin, B. G. Neel, et al., J. Biol. Chem. 281, 1746 (2006). PubMed ID: 16291744

Source:PTPN6Type of molecule:TyrPhosphatase Location:FAC
Target:ACTN1Type of molecule:Actinbundling Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. S. Y. Lin, S. Raval, Z. Zhang, et al., J. Biol. Chem. 279, 25755 (2004). PubMed ID: 15070900