Focal Adhesion Network Components

ACTB

Swiss-Prot Human Accession Code: P60709
List of interactions:

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:ABL1Type of molecule:TyrKinase Location:FAC
Type of interaction:Inhibition Effect:_
References:
1. et al., J. Cell. Biol. 124, 325 (1994). PubMed ID: 8294516

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:CTTNType of molecule:Actinbinding Location:FAC
Type of interaction:Binding Effect:0
References:
1. H. Wu, J. T. Parsons, J. Cell. Biol. 120, 1417 (1993). PubMed ID: 7680654

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:CSRP1Type of molecule:Cytoskeletal Location:FACA
Type of interaction:Binding Effect:0
References:
1. T. C. Tran, C. Singleton, T. S. Fraley, et al., BMC. Cell. Biol. 6, 45, (2005). PubMed ID: 16336664

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:VIL2Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. C. B. Shuster, I. M. Herman, J. Cell. Biol. 128, 837 (1995). PubMed ID: 7876308

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:FLNAType of molecule:ActinBinding Location:FAC
Type of interaction:Binding Effect:0
References:
1. K. Wang, S. J. Singer, Proc. Natl. Acad. Sci. U. S. A. 74, 2021 (1977). PubMed ID: 325564

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:HSPB1Type of molecule:Chaperone Location:FACA
Type of interaction:Binding Effect:0
References:
1. K. N. Bitar, Am. J. Physiol. Gastrointest. Liver. Physiol. 282, G894 (2002). PubMed ID: 11960785

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:LASP1Type of molecule:ActinBinding Location:FAC
Type of interaction:Binding Effect:0
References:
1. C. S. Chew, X. Chen, J. A. Parente, et al., J. Cell. Sci. 115, 4787 (2002). PubMed ID: 12432067

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:NEXNType of molecule:ActinBinding Location:FAC
Type of interaction:Binding Effect:0
References:
1. W. Wang, W. Zhang, Y. Han, et al., Biochem. Biophys. Res. Commun. 330, 1127 (2005). PubMed ID: 15823560

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:PAK1Type of molecule:SerThrKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. Dharmawardhane, L. C. Sanders, S. S. Martin, et al., J. Cell. Biol. 138, 1265 (1997). PubMed ID: 9298982

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:PARVAType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. N. Nikolopoulos, C. E. Turner, J. Cell. Biol. 151, 1435 (2001). PubMed ID: 11134073

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:PRKCAType of molecule:SerThrKinase Location:FAC
Type of interaction:Binding Effect:0
References:
1. N. D. Smallwood, B. S. Hausman, X. Wang, et al., Am. J. Physiol. Cell. Physiol. 288, C906 (2005). PubMed ID: 15590896

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:PLEC1Type of molecule:Cytoskeletal Location:FACA
Type of interaction:Binding Effect:0
References:
1. J. Sevcik, L. Urbanikova, J. Kost'an, et al., Eur. J. Biochem. 271, 1873 (2004). PubMed ID: 15128297

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:ARHGAP24Type of molecule:GAP Location:FAC
Type of interaction:Binding Effect:0
References:
1. I. Lavelin, B. Geiger, J. Biol. Chem. 280, 7178 (2005). PubMed ID: 15611138

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:TLN1Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Muguruma, S. Matsumura, T. Fukazawa, Biochem. Biophys. Res. Commun. 171, 1217 (1990). PubMed ID: 2121138

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:TNS1Type of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. S. H. Lo, P. A. Janmey, J. H. Hartwig, et al., J. Cell. Biol. 125, 1067 (1994). PubMed ID: 8195290

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:VCLType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. J. A. Wilkins, S. Lin, Cell. 28, 83 (1982). PubMed ID: 6802502

Source:ACTBType of molecule:Cytoskeletal Location:FAC
Target:PLD1Type of molecule:Phospholipase Location:FACA
Type of interaction:Inhibition Effect:_
References:
1. S. Lee, J. B. Park, J. H. Kim, et al., J. Biol. Chem. 276, 28252 (2001). PubMed ID: 11373276

Source:ACTN1Type of molecule:Actinbundling Location:FAC
Target:ACTBType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. W. Drabikowski, E. Nowak, Eur. J. Biochem. 5, 209 (1968). PubMed ID: 5667356

Source:ARPC2Type of molecule:ActinBinding Location:FACA
Target:ACTBType of molecule:Cytoskeletal Location:FAC
Type of interaction:Activation Effect:+
References:
1. R. D. Mullins, J. A. Heuser, T. D. Pollard, Proc. Natl. Acad. Sci. U. S. A. 95, 6181 (1998). PubMed ID: 9600938

Source:CFL1Type of molecule:ActinBinding Location:FACA
Target:ACTBType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. R. Nagaoka, H. Abe, T. Obinata, Cell. Motil. Cytoskeleton. 35, 200 (1997). PubMed ID: 8913641

Source:KEAP1Type of molecule:ActinBundling Location:FAC
Target:ACTBType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. I. Kang, A. Kobayashi, N. Wakabayashi, et al., Proc. Natl. Acad. Sci. U. S. A. 101, 2046 (2004). PubMed ID: 14764898

Source:PFN1Type of molecule:ActinBinding Location:FACA
Target:ACTBType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. L. Carlsson, L. E. Nystrom, I. Sundkvist, et al., J. Mol. Biol. 115, 465 (1978). PubMed ID: 563468

Source:VASPType of molecule:ActinBinding Location:FAC
Target:ACTBType of molecule:Cytoskeletal Location:FAC
Type of interaction:Binding Effect:0
References:
1. M. Reinhard, M. Halbrugge, U. Scheer, et al., EMBO. J. 11, 2063 (1992). PubMed ID: 1318192